diff --git a/atlas/templates/atlas/new_uploads.html b/atlas/templates/atlas/new_uploads.html
index 2d0dec84..671dffd5 100644
--- a/atlas/templates/atlas/new_uploads.html
+++ b/atlas/templates/atlas/new_uploads.html
@@ -67,7 +67,12 @@
     </div>
 
     <div id="selection-summary" class="alert alert-secondary py-2 mb-3 d-none"></div>
-    <div id="duplicate-progress" class="small text-muted mb-2"></div>
+    <div class="d-flex flex-wrap align-items-center gap-2 mb-2">
+        <div id="duplicate-progress" class="small text-muted"></div>
+        <button type="button" id="deselect-duplicates" class="btn btn-sm btn-outline-danger d-none">
+            <i class="bi bi-x-circle me-1"></i>Deselect all duplicates
+        </button>
+    </div>
 
     <div class="alert alert-warning d-none anon-alert" role="alert">
         <p class="mb-2">Potential anonymisation issues were detected. Flagged series are highlighted below.</p>
@@ -431,6 +436,7 @@
         function updateUploadButtonState() {
             const uploadButton = document.getElementById("uploadButton");
             const anonAlert = document.querySelector(".anon-alert");
+            const deselectDuplicatesBtn = document.getElementById("deselect-duplicates");
             const hasSelected = window.uploadPreview.records.some(r => r.include);
             const hasWarnings = hasAnonymisationWarnings();
             const hasDuplicates = window.uploadPreview.records.some(r => r.include && r.duplicate);
@@ -439,6 +445,9 @@
             window.uploadPreview.records.some((r) => r.include && !r.duplicateChecked);
 
             renderAnonymisationIssueSummary();
+            if (deselectDuplicatesBtn) {
+                deselectDuplicatesBtn.classList.toggle("d-none", !hasDuplicates);
+            }
 
             if (!hasSelected) {
                 uploadButton.disabled = true;
@@ -483,14 +492,36 @@
         }
 
         function getSeriesStatusClass(series) {
+            const includeCount = series.files.filter(f => f.include).length;
+            if (!includeCount) return "series-card excluded";
+
             const hasTagWarnings = series.files.some(f => f.tagWarnings.length > 0);
             const hasOcrWarnings = series.files.some(f => f.ocrWarning);
-            const hasDuplicates = series.files.some(f => f.duplicate);
+            const hasDuplicates = series.files.some(f => f.include && f.duplicate);
             if (hasTagWarnings || hasOcrWarnings) return "series-card warning";
             if (hasDuplicates) return "series-card duplicate";
             return "series-card";
         }
 
+        function deselectDuplicateSeries() {
+            const duplicateSeriesUids = new Set(
+                window.uploadPreview.records
+                    .filter((record) => record.include && record.duplicate)
+                    .map((record) => record.seriesUid)
+            );
+
+            if (!duplicateSeriesUids.size) {
+                toastr.info("No selected duplicate series to deselect.");
+                return;
+            }
+
+            duplicateSeriesUids.forEach((seriesUid) => applyIncludeToSeries(seriesUid, false));
+            window.uploadPreview.forceAnonymisationOverride = false;
+            scheduleDuplicateCheck();
+            renderGroupedPreview();
+            toastr.info(`Deselected ${duplicateSeriesUids.size} duplicate series.`);
+        }
+
         function renderGroupedPreview() {
             const groupedRoot = document.getElementById("preupload-grouped");
             const grouped = window.uploadPreview.grouped;
@@ -1264,6 +1295,10 @@
                 renderGroupedPreview();
             });
 
+            bindIfExists("deselect-duplicates", "click", () => {
+                deselectDuplicateSeries();
+            });
+
             bindIfExists("show-thumbnails", "change", () => {
                 renderGroupedPreview();
             });
@@ -1339,6 +1374,13 @@
             background: rgba(220, 53, 69, 0.08);
         }
 
+        .series-card.excluded {
+            border-color: rgba(148, 163, 184, 0.35);
+            background: rgba(148, 163, 184, 0.08);
+            opacity: 0.55;
+            filter: grayscale(0.25);
+        }
+
         .series-header {
             display: flex;
             justify-content: space-between;