Add comprehensive articles on Vascular Dementia and Wallerian Degeneration

- Created a detailed article for Vascular Dementia covering key facts, terminology, imaging findings, differential diagnoses, pathology, clinical issues, and diagnostic checklist.
- Developed an extensive article on Wallerian Degeneration including key facts, terminology, imaging features, differential diagnoses, pathology, clinical issues, and diagnostic checklist.
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title: "Attention Control Network"
docid: "a1bedda5-6478-40b2-98e7-6c5f5363b06f"
breadcrumbs:
- "Brain"
- "Anatomy"
- "Brain Network Anatomy"
- "Attention Control Network"
---
# IMAGING ANATOMY
- ## Overview
- Attention control network is a constellation of distributed brain networks processing attention to external stimuli and symbols
- Many aliases: Task-positive network, frontoparietal network, executive control network, and central executive network, each referring to subsets of the attention control network
- Terminology is not standard in the literature, and different authors use many of these terms interchangeably or to refer to different subsets of a broader attentional network
- ## Dorsal Attention Network
- Function: Voluntary control of attentional focus and goal-directed behavior
- Regions: Intraparietal sulcus, frontal eye fields, middle temporal, dorsolateral prefrontal cortex
- Intraparietal sulcus
- Weighting of sensory inputs: Direct control of relative "value" or "attention" to sensory stimuli
- Topographically organized by stimulus modality and spatial location
- Frontal eye fields and supplementary eye fields
- Control of direction of gaze to attentionally relevant stimuli
- Middle temporal (MT)
- Motion perception, dynamic features of attention
- Dorsolateral prefrontal cortex (DLPFC)
- Shared with ventral attention network, representations of objects and symbols, working memory
- ## Ventral Attention Network
- Function: Control of reorienting to relevant stimuli, working memory
- Aliases: Frontoparietal control network, executive control network
- Regions: Supramarginal and angular gyri, inferior frontal gyrus, dorsolateral prefrontal cortex, ventral anterior cingulate cortex
- Inferior parietal lobule (supramarginal and angular gyri)
- Inferior frontal gyrus
- DLPFC
- Ventral anterior cingulate cortex
- ## Salience Network
- Function: Detection of novel or salient stimuli
- Aliases: Novelty detection network, cingulo-opercular network
- Regions: Frontoinsula, dorsal anterior cingulate cortex
- Frontoinsula
- "Sensory" arm of salience network
- Mid superior insula: Detection of stimulus salience
- Mid inferior insula: Detection of emotive salience
- Anterior insula: Control of attention
- Dorsal anterior cingulate cortex
- "Motor" arm of salience network
- More anterior (pregenual) cingulate more associated with emotive salience, merges with ventral attention network
# ANATOMY IMAGING ISSUES
- ## Imaging Recommendations
- Specific subnetworks may be activated by specific tasks (e.g., oddball task for salience network, n-back task for dorsal attention network)
- ## Imaging Pitfalls
- Many fMRI tasks have differential stimulus attention between active and control conditions
- Activation in attentional regions may not be task specific, but a general consequence of differential attention between conditions
- ## Network Relationships
- Attention control network is anticorrelated to default mode network: When one is active, the other tends to be less active
- Allows focus of attention to shift between external and internal stimuli
- Gradients of anticorrelation across the attention control network are seen with specific subregions of each network hub showing greatest anticorrelation
- Attentional regions typically located in association cortex in regions spatially "equidistant" from primary sensory areas
- Flow of information from primary sensory to unimodal sensory association cortex to polymodal association cortex
# CLINICAL IMPLICATIONS
- ## Clinical Importance
- Right-dominant network for attention in most individuals
- Lesions of right ventral attention network may produce hemispatial neglect
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