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docs_md/articles/ahle_0ec0bca6-abee-4931-a6ed-43541b626261.md
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category: "Brain"
documentVersionId: "05d076c7-6110-4f03-952a-c22726d85e4d"
imageCount: 12
isBookmarked: false
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lastUpdated: "08/05/20"
pageDescription: "AHLE"
pageKeywords: "Brain, Diagnosis, Pathology-Based Diagnoses, Infectious, Inflammatory, and Demyelinating Disease, Inflammatory and Demyelinating Disease, AHLE"
pageTitle: "AHLE | STATdx"
enhancedTitle: "AHLE"
type: "DX"
references: true
breadcrumbs:
- "Brain"
- "Diagnosis"
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8f325204-5ce7-4da8-b816-cb545fa5b054
## References
# Selected References
1. [Mondia MWL et al: Acute hemorrhagic leukoencephalitis of Weston Hurst secondary to herpes encephalitis presenting as status epilepticus: a case report and review of literature. J Clin Neurosci. 67:265-70, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=31239199%5Bpmid%5D)
1. [Yae Y et al: Fulminant acute disseminated encephalomyelitis in children. Brain Dev. 41(4):373-7, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=30522797%5Bpmid%5D)
1. [Bonduelle T et al: Weston-Hurst syndrome with acute hemorrhagic cerebellitis. Clin Neurol Neurosurg. 173:118-9, 2018](http://www.ncbi.nlm.nih.gov/pubmed/?term=30121019%5Bpmid%5D)
1. [Fanou EM et al: Critical illness-associated cerebral microbleeds. Stroke. 48(4):1085-7, 2017](http://www.ncbi.nlm.nih.gov/pubmed/?term=28235962%5Bpmid%5D)
1. [Nabi S et al: Weston-Hurst syndrome: a rare fulminant form of acute disseminated encephalomyelitis (ADEM). BMJ Case Rep. 2016, 2016](http://www.ncbi.nlm.nih.gov/pubmed/?term=27797801%5Bpmid%5D)
1. [Jeganathan N et al: Acute hemorrhagic leukoencephalopathy associated with influenza A (H1N1) virus. Neurocrit Care. 19(2):218-21, 2013](http://www.ncbi.nlm.nih.gov/pubmed/?term=23943349%5Bpmid%5D)
## Images
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![Close-up view of autopsied brain in a patient with acute hemorrhagic leukoencephalitis (AHLE) shows innumerable tiny microbleeds in the subcortical and deep white matter (WM) <img src='/img/arrows/BO.png'/> and corpus callosum <img src='/img/arrows/BS.png'/>. Note the overlying cortex is almost completely spared <img src='/img/arrows/BC.png'/>. (Courtesy E. Rushing, MD.)](images/app.statdx.com_image_thumbnail_93f46c03-6a13-429c-9a24-57e552795482_size_168_quality_85_3867679d_20251018T070800Z.jpg)
*Close-up view of autopsied brain in a patient with acute hemorrhagic leukoencephalitis (AHLE) shows innumerable tiny microbleeds in the subcortical and deep white matter (WM) <img src='/img/arrows/BO.png'/> and corpus callosum <img src='/img/arrows/BS.png'/>. Note the overlying cortex is almost completely spared <img src='/img/arrows/BC.png'/>. (Courtesy E. Rushing, MD.)*
![Close-up view of autopsied brain in a patient with acute hemorrhagic leukoencephalitis (AHLE) shows innumerable tiny microbleeds in the subcortical and deep white matter (WM) <img src='/img/arrows/BO.png'/> and corpus callosum <img src='/img/arrows/BS.png'/>. Note the overlying cortex is almost completely spared <img src='/img/arrows/BC.png'/>. (Courtesy E. Rushing, MD.)](images/app.statdx.com_image_thumbnail_93f46c03-6a13-429c-9a24-57e552795482_size_174_quality_85_9e4b189a_20251018T095217Z.jpg)
![Close-up view of autopsied brain in a patient with acute hemorrhagic leukoencephalitis (AHLE) shows innumerable tiny microbleeds in the subcortical and deep white matter (WM) <img src='/img/arrows/BO.png'/> and corpus callosum <img src='/img/arrows/BS.png'/>. Note the overlying cortex is almost completely spared <img src='/img/arrows/BC.png'/>. (Courtesy E. Rushing, MD.)](images/app.statdx.com_image_thumbnail_93f46c03-6a13-429c-9a24-57e552795482_size_174_quality_85_88ff12ab_20251018T122441Z.jpg)
*Close-up view of autopsied brain in a patient with acute hemorrhagic leukoencephalitis (AHLE) shows innumerable tiny microbleeds in the subcortical and deep white matter (WM) <img src='/img/arrows/BO.png'/> and corpus callosum <img src='/img/arrows/BS.png'/>. Note the overlying cortex is almost completely spared <img src='/img/arrows/BC.png'/>. (Courtesy E. Rushing, MD.)*
![Axial FLAIR MR in a 28-year-old man with rapidly declining mental status after a flu-like illness shows patchy hyperintensities in the corpus callosum <img src='/img/arrows/WC.png'/> and deep/subcortical WM <img src='/img/arrows/WS.png'/>.](images/app.statdx.com_image_bc85bdf7-9d59-41a2-aa1c-4936434aeb8a_bb2e3243_20251018T070813Z.jpg)