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title: "Attention Control Network"
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docid: "a1bedda5-6478-40b2-98e7-6c5f5363b06f"
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breadcrumbs:
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- "Brain"
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- "Anatomy"
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- "Brain Network Anatomy"
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- "Attention Control Network"
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---
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# IMAGING ANATOMY
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- ## Overview
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- Attention control network is a constellation of distributed brain networks processing attention to external stimuli and symbols
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- Many aliases: Task-positive network, frontoparietal network, executive control network, and central executive network, each referring to subsets of the attention control network
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- Terminology is not standard in the literature, and different authors use many of these terms interchangeably or to refer to different subsets of a broader attentional network
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- ## Dorsal Attention Network
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- Function: Voluntary control of attentional focus and goal-directed behavior
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- Regions: Intraparietal sulcus, frontal eye fields, middle temporal, dorsolateral prefrontal cortex
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- Intraparietal sulcus
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- Weighting of sensory inputs: Direct control of relative "value" or "attention" to sensory stimuli
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- Topographically organized by stimulus modality and spatial location
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- Frontal eye fields and supplementary eye fields
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- Control of direction of gaze to attentionally relevant stimuli
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- Middle temporal (MT)
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- Motion perception, dynamic features of attention
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- Dorsolateral prefrontal cortex (DLPFC)
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- Shared with ventral attention network, representations of objects and symbols, working memory
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- ## Ventral Attention Network
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- Function: Control of reorienting to relevant stimuli, working memory
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- Aliases: Frontoparietal control network, executive control network
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- Regions: Supramarginal and angular gyri, inferior frontal gyrus, dorsolateral prefrontal cortex, ventral anterior cingulate cortex
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- Inferior parietal lobule (supramarginal and angular gyri)
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- Inferior frontal gyrus
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- DLPFC
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- Ventral anterior cingulate cortex
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- ## Salience Network
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- Function: Detection of novel or salient stimuli
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- Aliases: Novelty detection network, cingulo-opercular network
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- Regions: Frontoinsula, dorsal anterior cingulate cortex
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- Frontoinsula
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- "Sensory" arm of salience network
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- Mid superior insula: Detection of stimulus salience
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- Mid inferior insula: Detection of emotive salience
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- Anterior insula: Control of attention
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- Dorsal anterior cingulate cortex
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- "Motor" arm of salience network
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- More anterior (pregenual) cingulate more associated with emotive salience, merges with ventral attention network
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# ANATOMY IMAGING ISSUES
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- ## Imaging Recommendations
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- Specific subnetworks may be activated by specific tasks (e.g., oddball task for salience network, n-back task for dorsal attention network)
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- ## Imaging Pitfalls
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- Many fMRI tasks have differential stimulus attention between active and control conditions
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- Activation in attentional regions may not be task specific, but a general consequence of differential attention between conditions
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- ## Network Relationships
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- Attention control network is anticorrelated to default mode network: When one is active, the other tends to be less active
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- Allows focus of attention to shift between external and internal stimuli
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- Gradients of anticorrelation across the attention control network are seen with specific subregions of each network hub showing greatest anticorrelation
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- Attentional regions typically located in association cortex in regions spatially "equidistant" from primary sensory areas
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- Flow of information from primary sensory to unimodal sensory association cortex to polymodal association cortex
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# CLINICAL IMPLICATIONS
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- ## Clinical Importance
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- Right-dominant network for attention in most individuals
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- Lesions of right ventral attention network may produce hemispatial neglect
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