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title: "Intraventricular Obstructive Hydrocephalus"
docid: "eeac8d9b-1fdc-432e-8e09-11589611f7a8"
authors:
- key: "a25c450b-3d34-4f64-bba3-cc0834813df6"
value: "Miral D. Jhaveri, MD, MBA"
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name: "Brain"
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name: "Anatomy-Based Diagnoses"
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name: "Ventricles and Cisterns"
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name: "Hydrocephalus"
slug: "hydrocephalus"
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name: "Intraventricular Obstructive Hydrocephalus"
slug: "intraventricular-obstructive-hydro-"
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category: "Brain"
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documentVersionId: "102c8265-55ef-4963-964e-d8ed6d766992"
imageCount: 30
lastUpdated: "09/24/20"
pageDescription: "Intraventricular Obstructive Hydrocephalus"
pageKeywords: "Brain, Diagnosis, Anatomy-Based Diagnoses, Ventricles and Cisterns, Hydrocephalus, Intraventricular Obstructive Hydrocephalus"
pageTitle: "Intraventricular Obstructive Hydrocephalus | STATdx"
enhancedTitle: "Intraventricular Obstructive Hydrocephalus"
type: "DX"
references: true
breadcrumbs:
- "Brain"
- "Diagnosis"
- "Anatomy-Based Diagnoses"
- "Ventricles and Cisterns"
- "Hydrocephalus"
- "Intraventricular Obstructive Hydrocephalus"
---
# KEY FACTS
- ## Terminology
- Intraventricular obstructive hydrocephalus (IVOH) = obstruction proximal to foramina of Luschka, Magendie
- Acute IVOH (aIVOH)
- Chronic compensated IVOH (cIVOH)
- ## Imaging
- aIVOH = ballooned ventricles plus indistinct (blurred) margins
- "Fingers" of CSF extend into periventricular WM
- Most striking around ventricular horns (periventricular halos)
- After decompression, corpus callosum may show hyperintensity
- cIVOH = ballooned ventricles without periventricular halo
- ## Top Differential Diagnoses
- Ventricular enlargement secondary to parenchymal loss
- Normal-pressure hydrocephalus
- Extraventricular obstructive hydrocephalus
- Choroid plexus papilloma
- ## Pathology
- Intraventricular obstruction to CSF flow
- CSF production continues, ventricular pressure ↑
- Ventricles expand, compress adjacent parenchyma
- Periventricular interstitial fluid ↑
- Leads to myelin vacuolization, destruction
- Pathology varies depending on obstruction etiology
- ## Clinical Issues
- Varies with acuity, severity
- Headache, papilledema (aIVOH)
- Nausea, vomiting, diplopia (6th nerve palsy)
- ## Diagnostic Checklist
- Size of ventricles generally correlates poorly with intracranial pressure
# TERMINOLOGY
- ## Abbreviations
- Intraventricular obstructive hydrocephalus (IVOH)
- Acute IVOH (aIVOH)
- Chronic compensated IVOH (cIVOH)
- ## Synonyms
- Noncommunicating hydrocephalus
- ## Definitions
- Enlarged ventricles caused by physical obstruction at or proximal to 4th ventricular outflow foramina (of Luschka, Magendie)
# IMAGING
- ## General Features
- ### Best diagnostic clue
- aIVOH
- Ballooned ventricles with indistinct (blurred) margins
- cIVOH
- Ballooned ventricles without periventricular halo
- ### Size
- Bifrontal horn:intracranial diameter ratio > 0.3
- Temporal horn width > 3 mm
- ### Morphology
- Varies with site, duration of blockage
- Global/focally enlarged ventricle(s) ± ↑ intracranial pressure (ICP)
- Ventricles proximal to obstruction enlarge, appear more rounded
- Look for enlarged anterior recesses of 3rd ventricle
- ## CT Findings
- ### NECT
- Large ventricles proximal to obstruction
- aIVOH
- Ballooned ventricles with periventricular low-density halo
- cIVOH
- Ballooned ventricles without thick periventricular halo
- Basal cisterns, sulci compressed/obliterated
- ## MR Findings
- ### T1WI
- Lateral ventricles enlarged
- Corpus callosum (CC) thinned, stretched upward
- May be impinged against falx
- Impaction may cause pressure necrosis
- Fornix, internal cerebral veins (ICV) displaced downward
- Enlarged 3rd ventricle often herniated into expanded sella
- Funnel-shaped aqueduct of Sylvius in aqueductal stenosis
- ### T2WI
- aIVOH
- "Fingers" of CSF-like hyperintensity extend into periventricular white matter (WM), most striking around ventricular horns (periventricular halos)
- Disturbed/turbulent CSF flow
- Absent aqueductal flow void common
- CC may appear hyperintense
- cIVOH
- Large ventricles, normal CSF pressure
- No periventricular halo
- CC may show hyperintensity after decompression (15% of shunted IVOH cases)
- Thin-section T2WI, FIESTA, or CISS sequences
- Exquisitely delineate CSF spaces
- May demonstrate subtle abnormalities not detected on standard images
- ### FLAIR
- Fluid in periventricular halo does not suppress
- ### T1WI C+
- Neoplasm causing IVOH may enhance
- aIVOH may cause leptomeningeal vascular stasis, enhancement
- Can mimic meningitis, metastases
- ### MRS
- Small lactate resonances can be detected in up to 20% of CSF spaces, even if no hydrocephalus
- ## Other Modality Findings
- Contrast-enhanced ventriculography
- MR/CT used to identify site of obstruction, status of 3rd ventriculostomies
- MR can be used for assessing CSF flow
- Cardiac gated-phase contrast MR
- May show absent aqueductal CSF flow
- ## Imaging Recommendations
- ### Best imaging tool
- MR with contrast to evaluate cause of CSF obstruction
- ### Protocol advice
- 3D FEISTA/CISS
- ↓ CSF flow artifact
- Allows better delineation of ventricular contour, septa
- Sagittal high-resolution T2-weighted images
# DIFFERENTIAL DIAGNOSIS
- ## Ventricular Enlargement Secondary to Parenchymal Loss
- Old term: Ex vacuo hydrocephalus (not used)
- Age related (ventricular volume ↑ 1.2-1.4 mL after 60 years)
- Ischemia/infarction, trauma, infection, toxic
- Obtuse frontal angle (> 110°)
- Diffuse/focal enlargement of sulci, cisterns
- Normal lateral ventricles can be asymmetric (related to handedness, not sex)
- May correlate with some psychiatric disorders (e.g., schizophrenia)
- [Normal-Pressure Hydrocephalus](/document/normal-pressure-hydrocephalus/ba3f857d-58de-4f21-8463-1631b4cb9972)
- Progressive dementia, gait disturbance, incontinence
- Ventricular dilation with normal CSF pressure
- Sulci normal/minimally enlarged
- ↑ CSF displacement through aqueduct
- MRS shows lactate peak
- [Extraventricular Obstructive Hydrocephalus](/document/extraventricular-obstructive-hydro-/a0886d4c-f504-4165-bb52-2400e2385f68)
- Dilated ventricles due to mismatch between CSF formation, absorption
- ↓ CSF absorption through arachnoid villi
- Subarachnoid hemorrhage most common cause
- Others: Meningitis, carcinomatosis, granulomatous disease
- [Choroid Plexus Papilloma](/document/choroid-plexus-papilloma/18e712f5-8553-487d-a939-044336cbf0ad)
- Accounts for 2-5% of childhood intracranial tumors
- Child < 5 years with ↑ ICP
- Most common lateral ventricle trigone
- May overproduce CSF
- Hemorrhage, tumor spread may cause IVOH
- ## Longstanding Overt Ventriculomegaly in Adults
- Early childhood onset or longstanding progression of hydrocephalus into adulthood
- Markedly enlarged ventricles, high ICP
- ## Benign Enlargement of Subarachnoid Spaces and Ventricles
- Seen in association with macrocephaly in infants
- Not associated with developmental delay
# PATHOLOGY
- ## General Features
- ### Etiology
- Normal CSF production = ~ 0.4 mL/min, 500-600 mL/24 hrs
- Total volume of CSF in adult = 125-150 mL
- Intraventricular obstruction to CSF flow; as CSF production continues, ventricular fluid pressure ↑
- Ventricles expand, compress adjacent parenchyma; stretching may rupture/open ependymal cell junctions
- Periventricular interstitial fluid ↑ → myelin destruction
- Etiology depends on site
- Foramen of Monro
- Colloid cyst
- Subependymal nodule, tuberous sclerosis complex
- Subependymal giant cell astrocytoma
- 3rd ventricle
- Pituitary macroadenoma
- Craniopharyngioma
- Aqueduct of Sylvius
- Aqueductal stenosis
- Tectal glioma
- Pineal region tumors
- 4th ventricle
- Medulloblastoma, ependymoma
- Glioma, pilocytic astrocytoma, hemangioblastoma
- Cerebellar infarct
- Congenital anomalies (Chiari malformations, Dandy-Walker malformations, rhombencephalosynapsis)
- Metastasis, neurocysticercosis, or meningioma can occur at multiple intraventricular locations
- ### Genetics
- Cell adhesion molecule L1 (*L1CAM*) only gene recognized to cause congenital hydrocephalus
- Located on X chromosome (Xq28)
- Complications of hydrocephalus
- CC impingement syndrome
- Medial atrial diverticula
- ## Gross Pathologic & Surgical Features
- Focal/generalized ventricular enlargement
- Ependyma, adjacent WM are secondarily injured
- Variable pathology depending on causative factor
- ## Microscopic Features
- ↑ periventricular extracellular space
- Ependymal lining damaged or lost; surrounding WM becomes pale and rarefied
# CLINICAL ISSUES
- ## Presentation
- ### Most common signs/symptoms
- Varies with acuity, severity
- Headache, papilledema (aIVOH)
- Nausea, vomiting, diplopia (6th nerve palsy)
- ### Clinical profile
- Varies with etiology, severity, age of onset
- ## Demographics
- ### Age
- May be any age from in utero (congenital hydrocephalus) to adult
- ### Epidemiology
- Epidemiologic data varies widely, depending upon etiology and type of hydrocephalus
- ## Natural History & Prognosis
- Usually progressive unless treated
- ## Treatment
- Medical management to delay surgical intervention
- CSF diversion (shunt), endoscopic intervention, and ventriculostomy
- Surgery to alleviate primary cause of obstruction
- Most common neurosurgical procedure in children = CSF shunting for hydrocephalus
# DIAGNOSTIC CHECKLIST
- ## Consider
- Longstanding aqueductal stenosis can be caused by slow-growing tectal tumor
- Rarely, hydrocephalus caused by spinal tumor
- ## Image Interpretation Pearls
- Size of ventricles generally correlates poorly with ICP
- Pulsatile CSF may create confusing signal intensity, even mimic intraventricular mass
- Ventricular asymmetry can be normal variant
- If seen with absent septum pellucidum in fetus/neonate, look for vermis (r/o rhombencephalosynapsis)
5b1dd5dd-62fc-4446-8e5d-a43b8e65444e
## References
# Selected References
1. [Gholampour S et al: Comparing the efficiency of two treatment methods of hydrocephalus: shunt implantation and endoscopic third ventriculostomy. Basic Clin Neurosci. 10(3):185-98, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=31462974%5Bpmid%5D)
1. [Santiago-Dieppa DR et al: Obstructive hydrocephalus. N Engl J Med. 381(5):e10, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=31365804%5Bpmid%5D)
1. [Chellathurai A et al: Role of 3D SPACE sequence and susceptibility weighted imaging in the evaluation of hydrocephalus and treatment-oriented refined classification of hydrocephalus. Indian J Radiol Imaging. 28(4):385-94, 2018](http://www.ncbi.nlm.nih.gov/pubmed/?term=30662197%5Bpmid%5D)
1. [Hurni Y et al: Arrested hydrocephalus in childhood: case series and review of the literature. Neuropediatrics. 49(5):302-9, 2018](http://www.ncbi.nlm.nih.gov/pubmed/?term=29933461%5Bpmid%5D)
1. [Langner S et al: Diagnosis and differential diagnosis of hydrocephalus in adults. Rofo. 189(8):728-39, 2017](http://www.ncbi.nlm.nih.gov/pubmed/?term=28511266%5Bpmid%5D)
1. [Leinonen V et al: Cerebrospinal fluid circulation and hydrocephalus. Handb Clin Neurol. 145:39-50, 2017](http://www.ncbi.nlm.nih.gov/pubmed/?term=28987185%5Bpmid%5D)
1. [Algin O et al: Assessment of third ventriculostomy patency with the 3D-SPACE technique: a preliminary multicenter research study. J Neurosurg. 122(6):1347-55, 2015](http://www.ncbi.nlm.nih.gov/pubmed/?term=25859808%5Bpmid%5D)
1. [Russo N et al: Endoscopic approaches to intraventricular lesions. J Neurol Surg A Cent Eur Neurosurg. 76(5):353-60, 2015](http://www.ncbi.nlm.nih.gov/pubmed/?term=26008954%5Bpmid%5D)
1. [Flannery AM et al: Pediatric hydrocephalus: systematic literature review and evidence-based guidelines. Part 1: Introduction and methodology. J Neurosurg Pediatr. 14 Suppl 1:3-7, 2014](http://www.ncbi.nlm.nih.gov/pubmed/?term=25988777%5Bpmid%5D)
1. [Dinçer A et al: Radiologic evaluation of pediatric hydrocephalus. Childs Nerv Syst. 27(10):1543-62, 2011](http://www.ncbi.nlm.nih.gov/pubmed/?term=21928020%5Bpmid%5D)
1. [Mirone G et al: Hydrocephalus and spinal cord tumors: a review. Childs Nerv Syst. 27(10):1741-9, 2011](http://www.ncbi.nlm.nih.gov/pubmed/?term=21928038%5Bpmid%5D)
1. [Oi S: Classification of hydrocephalus: critical analysis of classification categories and advantages of "multi-categorical hydrocephalus classification" (Mc HC). Childs Nerv Syst. 27(10):1523-33, 2011](http://www.ncbi.nlm.nih.gov/pubmed/?term=21928018%5Bpmid%5D)
1. [Dinçer A et al: Is all "communicating" hydrocephalus really communicating? Prospective study on the value of 3D-constructive interference in steady state sequence at 3T. AJNR Am J Neuroradiol. 30(10):1898-906, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=19643921%5Bpmid%5D)
1. [Feng F et al: Evaluation of radionuclide cerebrospinal fluid scintigraphy as a guide in the management of patients with hydrocephalus. Clin Imaging. 33(2):85-9, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=19237049%5Bpmid%5D)
1. [Linninger AA et al: Normal and hydrocephalic brain dynamics: the role of reduced cerebrospinal fluid reabsorption in ventricular enlargement. Ann Biomed Eng. 37(7):1434-47, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=19373558%5Bpmid%5D)
1. [Oertel JM et al: Endoscopic third ventriculostomy in obstructive hydrocephalus due to giant basilar artery aneurysm. J Neurosurg. 110(1):14-8, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=18991498%5Bpmid%5D)
1. [Stoquart-El Sankari S et al: Phase-contrast MR imaging support for the diagnosis of aqueductal stenosis. AJNR Am J Neuroradiol. 30(1):209-14, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=18832663%5Bpmid%5D)
1. [Sekula RF Jr et al: A case of an elderly adult presenting with obstructive hydrocephalus secondary to a rare hemorrhagic suprasellar pilocytic astrocytoma. Clin Neuropathol. 27(6):396-9, 2008](http://www.ncbi.nlm.nih.gov/pubmed/?term=19130737%5Bpmid%5D)
1. [Yamada S et al: Visualization of cerebrospinal fluid movement with spin labeling at MR imaging: preliminary results in normal and pathophysiologic conditions. Radiology. 249(2):644-52, 2008](http://www.ncbi.nlm.nih.gov/pubmed/?term=18936318%5Bpmid%5D)
1. [Erdogan AR et al: Sex and handedness differences in size of cerebral ventricles of normal subjects. Int J Neurosci. 114(1):67-73, 2004](http://www.ncbi.nlm.nih.gov/pubmed/?term=14660068%5Bpmid%5D)
1. [Gaser C et al: Ventricular enlargement in schizophrenia related to volume reduction of the thalamus, striatum, and superior temporal cortex. Am J Psychiatry. 161(1):154-6, 2004](http://www.ncbi.nlm.nih.gov/pubmed/?term=14702264%5Bpmid%5D)
1. [Wyldes M et al: Isolated mild fetal ventriculomegaly. Arch Dis Child Fetal Neonatal Ed. 89(1):F9-13, 2004](http://www.ncbi.nlm.nih.gov/pubmed/?term=14711845%5Bpmid%5D)
1. [Akhondi H et al: Hydrocephalus as a presenting manifestation of neurosarcoidosis. South Med J. 96(4):403-6, 2003](http://www.ncbi.nlm.nih.gov/pubmed/?term=12916562%5Bpmid%5D)
1. [Bhattacharyya KB et al: Bobble-head doll syndrome: some atypical features with a new lesion and review of the literature. Acta Neurol Scand. 108(3):216-20, 2003](http://www.ncbi.nlm.nih.gov/pubmed/?term=12911467%5Bpmid%5D)
1. Brown KP et al: 1H MRS in human hydrocephalus. J MRI. 14:291-9, 2003
1. [Grunert P et al: The role of third ventriculostomy in the management of obstructive hydrocephalus. Minim Invasive Neurosurg. 46(1):16-21, 2003](http://www.ncbi.nlm.nih.gov/pubmed/?term=12640578%5Bpmid%5D)
1. [Joseph VB et al: MR ventriculography for the study of CSF flow. AJNR Am J Neuroradiol. 24(3):373-81, 2003](http://www.ncbi.nlm.nih.gov/pubmed/?term=12637285%5Bpmid%5D)
1. [Sener RN: Callosal changes in obstructive hydrocephalus: observations with FLAIR imaging, and diffusion MRI. Comput Med Imaging Graph. 26(5):333-7, 2002](http://www.ncbi.nlm.nih.gov/pubmed/?term=12204238%5Bpmid%5D)
## Images
### Selected Images
![Axial FLAIR MR in a patient with headache and vomiting demonstrates a colloid cyst at the foramen of Monro <img src='/img/arrows/CC.png'/> causing intraventricular obstructive hydrocephalus (IVOH) with dilatation of both lateral ventricles <img src='/img/arrows/CS.png'/>. Note thin rim of periventricular hyperintensity <img src='/img/arrows/CO.png'/> due to interstitial edema.](images/app.statdx.com_image_thumbnail_e5c174f6-9b00-41ca-b8e0-52124d6d5d33_annotated_true_size_900_quality_90_3aa6f8d6_20251018T164538Z.jpg)
*Axial FLAIR MR in a patient with headache and vomiting demonstrates a colloid cyst at the foramen of Monro <img src='/img/arrows/CC.png'/> causing intraventricular obstructive hydrocephalus (IVOH) with dilatation of both lateral ventricles <img src='/img/arrows/CS.png'/>. Note thin rim of periventricular hyperintensity <img src='/img/arrows/CO.png'/> due to interstitial edema.*
![Axial FLAIR MR in a patient with headache and vomiting demonstrates a colloid cyst at the foramen of Monro <img src='/img/arrows/CC.png'/> causing intraventricular obstructive hydrocephalus (IVOH) with dilatation of both lateral ventricles <img src='/img/arrows/CS.png'/>. Note thin rim of periventricular hyperintensity <img src='/img/arrows/CO.png'/> due to interstitial edema.](images/app.statdx.com_image_thumbnail_e5c174f6-9b00-41ca-b8e0-52124d6d5d33_size_174_quality_85_febe2249_20251018T155131Z.jpg)
*Axial FLAIR MR in a patient with headache and vomiting demonstrates a colloid cyst at the foramen of Monro <img src='/img/arrows/CC.png'/> causing intraventricular obstructive hydrocephalus (IVOH) with dilatation of both lateral ventricles <img src='/img/arrows/CS.png'/>. Note thin rim of periventricular hyperintensity <img src='/img/arrows/CO.png'/> due to interstitial edema.*
![Axial NECT in a patient with pineal region germinoma <img src='/img/arrows/CC.png'/> shows marked dilatation of the lateral ventricles <img src='/img/arrows/CO.png'/> and anterior 3rd ventricle <img src='/img/arrows/CS.png'/> with periventricular halo <img src='/img/arrows/WC.png'/> and diffuse effacement of the cortical sulci.](images/app.statdx.com_image_thumbnail_bb072fec-1cdc-4da0-8dfc-36cfc2a5a110_annotated_true_size_900_quality_90_6685e5f7_20251018T164538Z.jpg)
*Axial NECT in a patient with pineal region germinoma <img src='/img/arrows/CC.png'/> shows marked dilatation of the lateral ventricles <img src='/img/arrows/CO.png'/> and anterior 3rd ventricle <img src='/img/arrows/CS.png'/> with periventricular halo <img src='/img/arrows/WC.png'/> and diffuse effacement of the cortical sulci.*
![Coronal T1 C+ MR in a patient presenting with headache and ataxia demonstrates a large heterogeneously enhancing mass <img src='/img/arrows/CO.png'/> in the left cerebellum with mass effect and effacement of the 4th ventricle <img src='/img/arrows/CC.png'/>. Biopsy revealed a glioblastoma.](images/app.statdx.com_image_thumbnail_a4d9bbda-78d1-493c-baaf-b7ab31b10da6_annotated_true_size_900_quality_90_3651409b_20251018T164538Z.jpg)
*Coronal T1 C+ MR in a patient presenting with headache and ataxia demonstrates a large heterogeneously enhancing mass <img src='/img/arrows/CO.png'/> in the left cerebellum with mass effect and effacement of the 4th ventricle <img src='/img/arrows/CC.png'/>. Biopsy revealed a glioblastoma.*
![Axial FLAIR MR in the same patient shows marked dilatation of the lateral ventricles <img src='/img/arrows/CC.png'/> with extensive periventricular interstitial edema <img src='/img/arrows/CS.png'/> caused by compromised drainage of interstitial fluid or transependymal CSF migration.](images/app.statdx.com_image_thumbnail_2d8f3e24-47a1-4c45-9ecc-cebc09885e9d_annotated_true_size_900_quality_90_e373c7b5_20251018T164538Z.jpg)
*Axial FLAIR MR in the same patient shows marked dilatation of the lateral ventricles <img src='/img/arrows/CC.png'/> with extensive periventricular interstitial edema <img src='/img/arrows/CS.png'/> caused by compromised drainage of interstitial fluid or transependymal CSF migration.*
![Sagittal CISS MR in a patient with obstruction at the 4th ventricular outlet due to adhesions shows ballooning of the 4th ventricle <img src='/img/arrows/CO.png'/>, widening of the aqueduct of Sylvius <img src='/img/arrows/CC.png'/>, dilated 3rd and lateral ventricles with downward sloping of 3rd ventricular floor <img src='/img/arrows/CS.png'/>.](images/app.statdx.com_image_thumbnail_91c986f1-b192-4ee0-86ad-ed4014373565_annotated_true_size_900_quality_90_efdb7ec4_20251018T164538Z.jpg)
*Sagittal CISS MR in a patient with obstruction at the 4th ventricular outlet due to adhesions shows ballooning of the 4th ventricle <img src='/img/arrows/CO.png'/>, widening of the aqueduct of Sylvius <img src='/img/arrows/CC.png'/>, dilated 3rd and lateral ventricles with downward sloping of 3rd ventricular floor <img src='/img/arrows/CS.png'/>.*
![Axial FLAIR MR in a patient with tuberous sclerosis shows large subependymal giant cell astrocytoma <img src='/img/arrows/CS.png'/> causing obstructive hydrocephalus <img src='/img/arrows/CC.png'/> with mild periventricular edema <img src='/img/arrows/CO.png'/>. Note the subtle hyperintensity in the occipital lobe tuber <img src='/img/arrows/WO.png'/>.](images/app.statdx.com_image_thumbnail_e8bd350a-0dbd-4b07-a628-7ba634965a46_annotated_true_size_900_quality_90_49d18706_20251018T164538Z.jpg)
*Axial FLAIR MR in a patient with tuberous sclerosis shows large subependymal giant cell astrocytoma <img src='/img/arrows/CS.png'/> causing obstructive hydrocephalus <img src='/img/arrows/CC.png'/> with mild periventricular edema <img src='/img/arrows/CO.png'/>. Note the subtle hyperintensity in the occipital lobe tuber <img src='/img/arrows/WO.png'/>.*
![Sagittal CISS MR in a patient with aqueductal stenosis due to a thin web <img src='/img/arrows/CC.png'/> causing obstructive hydrocephalus is shown. High resolution thin-section T2 MR exquisitely delineates the CSF spaces and may demonstrate subtle abnormalities not detected on standard sequences.](images/app.statdx.com_image_thumbnail_ef27fe2f-6eef-4306-8752-89fecd5fc331_annotated_true_size_900_quality_90_4217aa29_20251018T164538Z.jpg)
*Sagittal CISS MR in a patient with aqueductal stenosis due to a thin web <img src='/img/arrows/CC.png'/> causing obstructive hydrocephalus is shown. High resolution thin-section T2 MR exquisitely delineates the CSF spaces and may demonstrate subtle abnormalities not detected on standard sequences.*
![Axial FLAIR MR in the same patient shows marked enlarged lateral ventricles <img src='/img/arrows/CO.png'/> with a very thin periventricular hyperintense rim <img src='/img/arrows/CC.png'/> and no sulcal effacement due to chronic compensated IVOH.](images/app.statdx.com_image_thumbnail_ec7e804b-5c09-4235-8429-ee0dc4fc2a7f_annotated_true_size_900_quality_90_cf502530_20251018T164538Z.jpg)
*Axial FLAIR MR in the same patient shows marked enlarged lateral ventricles <img src='/img/arrows/CO.png'/> with a very thin periventricular hyperintense rim <img src='/img/arrows/CC.png'/> and no sulcal effacement due to chronic compensated IVOH.*
![Axial FLAIR MR in a patient with IVOH shows an ependymal cyst <img src='/img/arrows/CC.png'/> at the foramen of Monro with asymmetric dilatation of the lateral ventricles, L &gt; R. There is marked bulging of the medial wall <img src='/img/arrows/CO.png'/> of the left lateral ventricle.](images/app.statdx.com_image_thumbnail_cb3411d0-41c7-433a-97e3-f121306cf24f_annotated_true_size_900_quality_90_069d90f2_20251018T164538Z.jpg)
*Axial FLAIR MR in a patient with IVOH shows an ependymal cyst <img src='/img/arrows/CC.png'/> at the foramen of Monro with asymmetric dilatation of the lateral ventricles, L &gt; R. There is marked bulging of the medial wall <img src='/img/arrows/CO.png'/> of the left lateral ventricle.*
![Sagittal T1 MR in the same patient demonstrates the large medial atrial diverticula <img src='/img/arrows/CC.png'/>, which herniates inferiorly through the tentorial incisura into the posterior fossa, compressing the vermis <img src='/img/arrows/CO.png'/>, tectal plate <img src='/img/arrows/CS.png'/>, aqueduct, and 4th ventricle <img src='/img/arrows/WC.png'/>.](images/app.statdx.com_image_thumbnail_9d4aeb38-2745-4513-9b2b-e51d38e60ec2_annotated_true_size_900_quality_90_efd2d55e_20251018T165016Z.jpg)
*Sagittal T1 MR in the same patient demonstrates the large medial atrial diverticula <img src='/img/arrows/CC.png'/>, which herniates inferiorly through the tentorial incisura into the posterior fossa, compressing the vermis <img src='/img/arrows/CO.png'/>, tectal plate <img src='/img/arrows/CS.png'/>, aqueduct, and 4th ventricle <img src='/img/arrows/WC.png'/>.*
### Additional Images
![Sagittal T1WI MR shows large mass within the 4th ventricle <img src='/img/arrows/BO.png'/> causing IVOH or noncommunicating hydrocephalus.](images/app.statdx.com_image_thumbnail_111173b4-2ccd-4d7a-9423-8ea7a67d3faa_annotated_true_size_900_quality_90_db7227b6_20251018T165016Z.jpg)
*Sagittal T1WI MR shows large mass within the 4th ventricle <img src='/img/arrows/BO.png'/> causing IVOH or noncommunicating hydrocephalus.*
![Sagittal T2WI MR in the same patient shows transependymal CSF flow, seen here as &quot;fingers&quot; extending into white matter around the enlarged lateral ventricle. The case was medulloblastoma with acute IVOH.](images/app.statdx.com_image_thumbnail_0096a55e-9e96-409e-ac0f-01c95f3d26bb_annotated_true_size_900_quality_90_b7750d59_20251018T165017Z.jpg)
*Sagittal T2WI MR in the same patient shows transependymal CSF flow, seen here as &quot;fingers&quot; extending into white matter around the enlarged lateral ventricle. The case was medulloblastoma with acute IVOH.*
![Coronal T1 C+ MR shows IVOH with a large enhancing intraventricular mass <img src='/img/arrows/BS.png'/> causing marked enlargement of the lateral ventricles <img src='/img/arrows/WS.png'/>.](images/app.statdx.com_image_thumbnail_df9fd7e5-2974-4621-9d50-efceebb95d70_annotated_true_size_900_quality_90_ada0f1a6_20251018T165016Z.jpg)
*Coronal T1 C+ MR shows IVOH with a large enhancing intraventricular mass <img src='/img/arrows/BS.png'/> causing marked enlargement of the lateral ventricles <img src='/img/arrows/WS.png'/>.*
![Axial NECT in the same patient shows the large intraventricular mass <img src='/img/arrows/BS.png'/> within the 4th ventricle. Note the dilated temporal horns <img src='/img/arrows/WS.png'/>.](images/app.statdx.com_image_thumbnail_5e46b562-c694-4b32-a46c-af0d64e8c289_annotated_true_size_900_quality_90_9842d1b3_20251018T165016Z.jpg)
*Axial NECT in the same patient shows the large intraventricular mass <img src='/img/arrows/BS.png'/> within the 4th ventricle. Note the dilated temporal horns <img src='/img/arrows/WS.png'/>.*
![Sagittal T1WI MR shows IVOH secondary to aqueductal stenosis and distal stenosis of cerebral aqueduct <img src='/img/arrows/BC.png'/>. Note the enlarged lateral and 3rd ventricles.](images/app.statdx.com_image_thumbnail_59c0d666-8b8b-4f34-881e-7578f851fa7f_annotated_true_size_900_quality_90_ac9b7114_20251018T165016Z.jpg)
*Sagittal T1WI MR shows IVOH secondary to aqueductal stenosis and distal stenosis of cerebral aqueduct <img src='/img/arrows/BC.png'/>. Note the enlarged lateral and 3rd ventricles.*
![Axial FLAIR MR shows neurosarcoidosis and IVOH secondary to diffuse meningeal disease. Periventricular white matter hyperintensities <img src='/img/arrows/BS.png'/> are also present, as well as choroid involvement <img src='/img/arrows/WO.png'/>.](images/app.statdx.com_image_thumbnail_32fe8687-87ee-4698-81ba-308f84e4409a_annotated_true_size_900_quality_90_6ebf3bdd_20251018T165017Z.jpg)
*Axial FLAIR MR shows neurosarcoidosis and IVOH secondary to diffuse meningeal disease. Periventricular white matter hyperintensities <img src='/img/arrows/BS.png'/> are also present, as well as choroid involvement <img src='/img/arrows/WO.png'/>.*
![Coronal T1 C+ MR shows neurocysticercosis involvement within the 3rd ventricle and aqueduct <img src='/img/arrows/BS.png'/>, causing IVOH. The lateral ventricles are dilated.](images/app.statdx.com_image_thumbnail_30290860-d589-4878-ab88-f2e5114f4116_annotated_true_size_900_quality_90_d81df3a5_20251018T165017Z.jpg)
*Coronal T1 C+ MR shows neurocysticercosis involvement within the 3rd ventricle and aqueduct <img src='/img/arrows/BS.png'/>, causing IVOH. The lateral ventricles are dilated.*
![Axial FLAIR MR shows neurocysticercosis resulting in IVOH. Large intraventricular cysts are present in the lateral vents <img src='/img/arrows/BS.png'/>, obstructing the foramina of Monro.](images/app.statdx.com_image_thumbnail_7bbd2516-73b7-45fb-b5ff-9f306d6d3a80_annotated_true_size_900_quality_90_09e03021_20251018T165016Z.jpg)
*Axial FLAIR MR shows neurocysticercosis resulting in IVOH. Large intraventricular cysts are present in the lateral vents <img src='/img/arrows/BS.png'/>, obstructing the foramina of Monro.*
![Axial T1WI MR shows a well-defined, hyperintense lesion <img src='/img/arrows/BO.png'/> at the foramen of Monro in a patient with headaches, most consistent with a colloid cyst. Note the enlargement of the lateral ventricles <img src='/img/arrows/BC.png'/> due to obstruction at the foramen of Monro.](images/app.statdx.com_image_thumbnail_7ae9f42a-db38-4524-b7c0-79d52b798e21_annotated_true_size_900_quality_90_67db5fbc_20251018T165016Z.jpg)
*Axial T1WI MR shows a well-defined, hyperintense lesion <img src='/img/arrows/BO.png'/> at the foramen of Monro in a patient with headaches, most consistent with a colloid cyst. Note the enlargement of the lateral ventricles <img src='/img/arrows/BC.png'/> due to obstruction at the foramen of Monro.*
![Sagittal T1WI C+ MR shows a homogeneously enhancing mass in the posterior 3rd ventricle <img src='/img/arrows/WO.png'/>, which causes obstruction and dilatation of the lateral and 3rd ventricles. On pathology, this was an astrocytoma.](images/app.statdx.com_image_thumbnail_a6d2a9a8-b74a-495d-8445-9c79b3030f4d_annotated_true_size_900_quality_90_54985e0c_20251018T165017Z.jpg)
*Sagittal T1WI C+ MR shows a homogeneously enhancing mass in the posterior 3rd ventricle <img src='/img/arrows/WO.png'/>, which causes obstruction and dilatation of the lateral and 3rd ventricles. On pathology, this was an astrocytoma.*
![Coronal T2WI MR shows a pilocytic astrocytoma centered in the right thalamus <img src='/img/arrows/CO.png'/> causing severe mass effect on the 3rd ventricle <img src='/img/arrows/CS.png'/> and resultant obstructive hydrocephalus <img src='/img/arrows/WC.png'/>.](images/app.statdx.com_image_thumbnail_80232788-db60-4f4f-895b-3180811f62b7_annotated_true_size_900_quality_90_9f55a6f6_20251018T165017Z.jpg)
*Coronal T2WI MR shows a pilocytic astrocytoma centered in the right thalamus <img src='/img/arrows/CO.png'/> causing severe mass effect on the 3rd ventricle <img src='/img/arrows/CS.png'/> and resultant obstructive hydrocephalus <img src='/img/arrows/WC.png'/>.*
![Axial T2WI MR demonstrates a well-defined CSF intensity cyst with the left temporal horn most consistent with an ependymal cyst <img src='/img/arrows/BO.png'/>. Note the dilated and trapped left temporal horn <img src='/img/arrows/BS.png'/>.](images/app.statdx.com_image_thumbnail_66d7ab24-8ae0-472b-9313-305394ec4c03_annotated_true_size_900_quality_90_29d87168_20251018T165017Z.jpg)
*Axial T2WI MR demonstrates a well-defined CSF intensity cyst with the left temporal horn most consistent with an ependymal cyst <img src='/img/arrows/BO.png'/>. Note the dilated and trapped left temporal horn <img src='/img/arrows/BS.png'/>.*
![Sagittal T1WI C+ MR shows an enhancing mass in the pineal region <img src='/img/arrows/BS.png'/> causing mass effect on the tectal plate and aqueductal obstruction. Note the extensive leptomeningeal enhancement due to CSF spread of tumor. CSF cytology showed a primitive neuroectodermal tumor.](images/app.statdx.com_image_thumbnail_13465a11-c0bb-4055-8c14-056ea999ea83_annotated_true_size_900_quality_90_d6a81efb_20251018T165017Z.jpg)
*Sagittal T1WI C+ MR shows an enhancing mass in the pineal region <img src='/img/arrows/BS.png'/> causing mass effect on the tectal plate and aqueductal obstruction. Note the extensive leptomeningeal enhancement due to CSF spread of tumor. CSF cytology showed a primitive neuroectodermal tumor.*
![Axial T2WI MR in a patient with corpus callosum impingement syndrome, after shunting for severe IVOH, shows a shunt tube <img src='/img/arrows/WC.png'/>, bilateral subdural fluid collections, and striated hyperintensity in the corpus callosum <img src='/img/arrows/BS.png'/> with somewhat less striking changes in the periventricular white matter <img src='/img/arrows/WO.png'/>. (Courtesy S. Candy, MD.)](images/app.statdx.com_image_thumbnail_e3c1a91c-c335-42df-baed-81b3ef83e867_annotated_true_size_900_quality_90_90e63be0_20251018T165017Z.jpg)
*Axial T2WI MR in a patient with corpus callosum impingement syndrome, after shunting for severe IVOH, shows a shunt tube <img src='/img/arrows/WC.png'/>, bilateral subdural fluid collections, and striated hyperintensity in the corpus callosum <img src='/img/arrows/BS.png'/> with somewhat less striking changes in the periventricular white matter <img src='/img/arrows/WO.png'/>. (Courtesy S. Candy, MD.)*
![Axial NECT in a patient with headache demonstrates a classic colloid cyst at the foramen of Monro <img src='/img/arrows/CC.png'/> causing IVOH with dilatation of both lateral ventricles <img src='/img/arrows/CS.png'/>. Note the periventricular hypodensities <img src='/img/arrows/CO.png'/> due to transependymal leakage of CSF.](images/app.statdx.com_image_thumbnail_5272a7c9-5ae5-4498-bff6-256abf29b99a_annotated_true_size_900_quality_90_d97a420a_20251018T165017Z.jpg)
*Axial NECT in a patient with headache demonstrates a classic colloid cyst at the foramen of Monro <img src='/img/arrows/CC.png'/> causing IVOH with dilatation of both lateral ventricles <img src='/img/arrows/CS.png'/>. Note the periventricular hypodensities <img src='/img/arrows/CO.png'/> due to transependymal leakage of CSF.*
![Axial CECT demonstrates a subacute left posterior inferior cerebellar infarct <img src='/img/arrows/CS.png'/> causing mass effect on the 4th ventricle <img src='/img/arrows/CC.png'/> and resulting in obstructive hydrocephalus <img src='/img/arrows/CO.png'/>.](images/app.statdx.com_image_thumbnail_7b359f58-dd44-4486-b7e0-8d172de6aece_annotated_true_size_900_quality_90_baccaab2_20251018T165017Z.jpg)
*Axial CECT demonstrates a subacute left posterior inferior cerebellar infarct <img src='/img/arrows/CS.png'/> causing mass effect on the 4th ventricle <img src='/img/arrows/CC.png'/> and resulting in obstructive hydrocephalus <img src='/img/arrows/CO.png'/>.*
![Axial FLAIR MR shows massive enlargement of the 3rd and lateral ventricles by a CSF-like mass within the 3rd ventricle <img src='/img/arrows/WS.png'/>. There is periventricular interstitial edema <img src='/img/arrows/WO.png'/>. At surgery, an ependymal cyst of the 3rd ventricle was found and fenestrated.](images/app.statdx.com_image_thumbnail_5623057c-c423-4d4c-9801-45283be9a3dd_annotated_true_size_900_quality_90_b5086e29_20251018T165017Z.jpg)
*Axial FLAIR MR shows massive enlargement of the 3rd and lateral ventricles by a CSF-like mass within the 3rd ventricle <img src='/img/arrows/WS.png'/>. There is periventricular interstitial edema <img src='/img/arrows/WO.png'/>. At surgery, an ependymal cyst of the 3rd ventricle was found and fenestrated.*
![Sagittal T1 MR shows a large arachnoid cyst <img src='/img/arrows/CC.png'/> in the superior cerebellar cistern causing severe mass effect on the tectal plate <img src='/img/arrows/CS.png'/> and aqueduct <img src='/img/arrows/WC.png'/>.There is dilatation of the 3rd and lateral ventricles with thinning of the corpus callosum <img src='/img/arrows/CO.png'/>.](images/app.statdx.com_image_thumbnail_4805b47b-9b84-4da7-9efa-e16c8cefdcf8_annotated_true_size_900_quality_90_039b4f28_20251018T165017Z.jpg)
*Sagittal T1 MR shows a large arachnoid cyst <img src='/img/arrows/CC.png'/> in the superior cerebellar cistern causing severe mass effect on the tectal plate <img src='/img/arrows/CS.png'/> and aqueduct <img src='/img/arrows/WC.png'/>.There is dilatation of the 3rd and lateral ventricles with thinning of the corpus callosum <img src='/img/arrows/CO.png'/>.*
![Sagittal T1WI C+ MR shows a cyst <img src='/img/arrows/WS.png'/> with an enhancing mural nodule <img src='/img/arrows/WO.png'/> of hemangioblastoma in the vermis, causing severe effacement of the 4th ventricle <img src='/img/arrows/WC.png'/> and obstructive hydrocephalus.](images/app.statdx.com_image_thumbnail_519a5b7e-6869-4b93-98f6-a6edefac58a8_annotated_true_size_900_quality_90_d8758d1c_20251018T165017Z.jpg)
*Sagittal T1WI C+ MR shows a cyst <img src='/img/arrows/WS.png'/> with an enhancing mural nodule <img src='/img/arrows/WO.png'/> of hemangioblastoma in the vermis, causing severe effacement of the 4th ventricle <img src='/img/arrows/WC.png'/> and obstructive hydrocephalus.*
![Sagittal T2 MR demonstrates an enlarged T2 hyperintense tectal plate glioma <img src='/img/arrows/CC.png'/>, which causes obstruction at the aqueduct and dilatation of the lateral <img src='/img/arrows/CS.png'/> and 3rd ventricles <img src='/img/arrows/CO.png'/>.](images/app.statdx.com_image_thumbnail_7ca87971-568b-4324-bd66-b820c656d469_annotated_true_size_900_quality_90_0c6bf4c7_20251018T165017Z.jpg)
*Sagittal T2 MR demonstrates an enlarged T2 hyperintense tectal plate glioma <img src='/img/arrows/CC.png'/>, which causes obstruction at the aqueduct and dilatation of the lateral <img src='/img/arrows/CS.png'/> and 3rd ventricles <img src='/img/arrows/CO.png'/>.*