--- title: "Narrowed Aorta" docid: "763503a4-a7b8-4aff-8846-3dfbe312125c" authors: - key: "df804626-c042-4296-96e3-836a6da50fd6" value: "Gregory Kicska, MD, PhD" breadcrumbs: - name: "Cardiac" slug: "cardiac" treeNodeId: "fa90100b-619c-430e-8074-b5b9789bab39" - name: "Differential Diagnosis" slug: "differential-diagnosis" treeNodeId: "952326a0-b3ea-4a21-aa7a-d796cc9325ed" - name: "Narrowed Aorta" slug: "narrowed-aorta" treeNodeId: null category: "Cardiac" documentVersionId: "d3c26ea4-8f08-4b3c-8e42-c5d40e18e83c" imageCount: 9 lastUpdated: "03/17/22" pageDescription: "Narrowed Aorta" pageKeywords: "Cardiac, Differential Diagnosis, Narrowed Aorta" pageTitle: "Narrowed Aorta | STATdx" enhancedTitle: "Narrowed Aorta" type: "DDX" breadcrumbs: - "Cardiac" - "Differential Diagnosis" - "Narrowed Aorta" --- # ESSENTIAL INFORMATION - ## Key Differential Diagnosis Issues - Focal outer diameter narrowed in coarctation or vasculitis - Normative data should be consulted to exclude common pitfall of misinterpreting normal aortic dimension for small body as abnormal - For > 45 years, aorta considered abnormally small if diameter at level of main pulmonary artery < 24 mm for ascending and < 18 mm for descending aorta - Larger diameters may still be abnormal if older age, larger body surface area (BSA), or male patient - Luminal diameter narrowing in atherosclerosis, aortic thrombus, and sarcoma - ## Helpful Clues for Common Diagnoses - **Coarctation of Aorta** - Focal narrowing occurs below ductus arterious in adults, at ductus arterious with arch hypoplasia in neonates - Dilated collaterals (intercostal, internal thoracic) indicate hemodynamically significant coarctation - Treated coarctation patients can have restenosis - Associated with bicuspid aortic valve, Turner syndrome, Marfan syndrome - **Pseudo-coarctation** - Redundant aorta with narrowing distal to left subclavian origin without hemodynamic effect - No rib notching, cardiomegaly, or collateral vessels - Dilated brachiocephalic artery and high arch often present - ## Helpful Clues for Less Common Diagnoses - **Corral Reef Aorta** - "Rock hard" calcific atherosclerotic plaque protruding into lumen of abdominal aorta - Bizarre shape of protrusions resemble corals - **Leriche Syndrome** - Aortoiliac occlusive disease due to severe atherosclerosis of distal abdominal aorta and ileo-femoral arteries - Presenting symptom triad in chronic variant: Claudication, absent femoral pulses, erectile dysfunction - **Large Vessel Vasculitis** - Variable segment length narrowing - Branch vessel narrowing is common - Periaortic thickening and enhancement - Periaortic FDG uptake implies active disease - Patient < 40 years of age implies Takayasu, patient > 40 years of age implies giant cell arteritis - ## Helpful Clues for Rare Diagnoses - **Extrinsic Aortic Compression** - Retroperitoneal fibrosis, neurofibromatosis, sarcomas, other neoplasms - **Aortic Sarcoma** - Rare mesenchymal neoplasms arising from aortic tissue and may protrude into and narrow aortic lumen - Angiosarcoma, leiomyosarcoma, fibrosarcoma, hemangioendothelioma, and myxoid sarcomas have been reported ## Images ### Selected Images ![PA radiograph shows subtle areas of rib notching . Note the rapid narrowing of the proximal descending thoracic aorta , which then returns to normal size more distally .](images/app.statdx.com_image_thumbnail_bc3bf664-51c7-420c-b430-4d6916a855f9_annotated_true_size_900_quality_90_f10d096da5fdf9b00bf048692c69fa28dff74204.jpg) **Coarctation of Aorta** *PA radiograph shows subtle areas of rib notching . Note the rapid narrowing of the proximal descending thoracic aorta , which then returns to normal size more distally .* ![PA radiograph shows subtle areas of rib notching . Note the rapid narrowing of the proximal descending thoracic aorta , which then returns to normal size more distally .](images/app.statdx.com_image_thumbnail_bc3bf664-51c7-420c-b430-4d6916a855f9_size_174_quality_85_4e11019138a63194d4d8baaa68bd1c32c1963d6a.jpg) **Coarctation of Aorta** *PA radiograph shows subtle areas of rib notching . Note the rapid narrowing of the proximal descending thoracic aorta , which then returns to normal size more distally .* ![Sagittal multiplanar CT reformat in the same patient shows focal narrowing of the aorta distal to the ductus arteriosus . Prominent collaterals were present (not shown).](images/app.statdx.com_image_thumbnail_206f362a-05a7-4e76-9d15-c093a0f3a0a4_annotated_true_size_900_quality_90_1696b8de6283b478789bcdab3c84897dd30953ec.jpg) **Coarctation of Aorta** *Sagittal multiplanar CT reformat in the same patient shows focal narrowing of the aorta distal to the ductus arteriosus . Prominent collaterals were present (not shown).* ![Sagittal oblique NECT shows focal mild narrowing of the aorta in a patient with pseudo-coarctation. The aorta appears redundant. No collateral vessels were present.](images/app.statdx.com_image_thumbnail_d566eed0-181c-4347-a644-59636da7bb66_annotated_true_size_900_quality_90_f95e9e102c14f676ef0eaa39744aa24f52466060.jpg) **Pseudo-coarctation** *Sagittal oblique NECT shows focal mild narrowing of the aorta in a patient with pseudo-coarctation. The aorta appears redundant. No collateral vessels were present.* ![Axial CECT shows extrinsic compression of the aorta by retroperitoneal soft tissue in a patient with retroperitoneal fibrosis.](f5df5335-eda0-4a73-9e2c-af871b7816cd) **Extrinsic Aortic Compression** *Axial CECT shows extrinsic compression of the aorta by retroperitoneal soft tissue in a patient with retroperitoneal fibrosis.* ![Coronal oblique contrast-enhanced MRA shows a diffusely narrowed aorta occlusion of the superior mesenteric artery . Note reconstituted SMA .](images/app.statdx.com_image_thumbnail_0f036a0c-50e4-44bd-8378-3fc76fd92930_annotated_true_size_900_quality_90_120ba3d8d20ccd90183034dabe24bbb30b844017.jpg) **Large Vessel Vasculitis** *Coronal oblique contrast-enhanced MRA shows a diffusely narrowed aorta occlusion of the superior mesenteric artery . Note reconstituted SMA .* ![Sagittal oblique MIP MRA in a patient with Takayasu arteritis shows tapered narrowing of the mid-descending thoracic aorta . Celiac artery origin stenosis is also present .](images/app.statdx.com_image_thumbnail_a35e02ef-fd12-4e84-a9a6-387c4becbf24_annotated_true_size_900_quality_90_7c95f98abb06ba9b84928d15c79ddcf7e656c570.jpg) **Large Vessel Vasculitis** *Sagittal oblique MIP MRA in a patient with Takayasu arteritis shows tapered narrowing of the mid-descending thoracic aorta . Celiac artery origin stenosis is also present .* ![Sagittal oblique MIP CECT shows tapered narrowing of the mid-descending aorta with wall thickening in a patient with Takayasu arteritis. Note the absence of atherosclerotic disease.](images/app.statdx.com_image_thumbnail_d54bd5ca-39ff-4f22-8732-412e1dd69d1e_annotated_true_size_900_quality_90_bff0aa5ef20a0cbdc557c8256fa7d14f9f3d401f.jpg) **Large Vessel Vasculitis** *Sagittal oblique MIP CECT shows tapered narrowing of the mid-descending aorta with wall thickening in a patient with Takayasu arteritis. Note the absence of atherosclerotic disease.* ![Axial CECT shows a narrowed aorta with circumferential wall thickening . Branch vessel stenoses were also present. This patient was > 40 years of age and was diagnosed with giant cell arteritis.](images/app.statdx.com_image_thumbnail_15fcbefa-4bbe-4015-b011-399741152e1e_annotated_true_size_900_quality_90_060cc52f35a63df82a061d07d37842d2f83dfe7b.jpg) **Large Vessel Vasculitis** *Axial CECT shows a narrowed aorta with circumferential wall thickening . Branch vessel stenoses were also present. This patient was > 40 years of age and was diagnosed with giant cell arteritis.* ### Additional Images ![Coronal CECT shows tapered narrowing of the mid-descending thoracic aorta in a patient with Takayasu arteritis.](images/app.statdx.com_image_thumbnail_42cf14d6-fb3e-4ccb-9144-a6dca1fdf92f_annotated_true_size_900_quality_90_07988c00ea232842f6dfbcf6900f58c01bc20193.jpg) **Large Vessel Vasculitis** *Coronal CECT shows tapered narrowing of the mid-descending thoracic aorta in a patient with Takayasu arteritis.*