feat: Add new articles on Allergic Bronchopulmonary Aspergillosis, Finger-in-Glove Sign, and Tracheal Dilatation; update content index and document conversion script
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title: "Allergic Bronchopulmonary Aspergillosis"
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docid: "81c5db2f-b8f6-4092-bcd2-ffb8aa3ab18a"
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breadcrumbs:
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- "Chest"
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- "Differential Diagnosis"
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- "Airways"
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- "General Imaging Patterns"
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- "Finger-in-Glove Sign"
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---
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# ESSENTIAL INFORMATION
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- ## Key Differential Diagnosis Issues
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- Finger-in-glove sign: Mucoid impaction with resultant dilated or impacted bronchi
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- Bronchial obstruction: Atresia, foreign body, neoplasm
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- Nonobstructive entities: Allergic bronchopulmonary aspergillosis, cystic fibrosis
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- Radiography/CT: Branching tubular opacities that typically radiate from hilum toward lung periphery
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- Differential diagnosis of bronchial branching tubular opacities
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- Arteriovenous malformation
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- Exhibits contrast enhancement
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- Demonstrates afferent and efferent vessels: Feeding artery(ies) and draining vein(s)
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- ## Helpful Clues for Common Diagnoses
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- **Allergic Bronchopulmonary Aspergillosis**
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- Immunologic disorder caused by hypersensitivity to*Aspergillus fumigatus*
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- Predisposing conditions: Asthma, cystic fibrosis
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- Laboratory findings: Positive aspergillus skin test, elevated IgE levels against *Aspergillus fumigatus*
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- Total IgE levels > 1,000 IU/mL
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- IgG antibodies against*A. fumigatus* in serum
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- Total eosinophil count > 500 cells/mL
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- Imaging: Branching tubular opacities, high attenuation on CT due to intrinsic calcium oxalate
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- **Congenital Bronchial Atresia**
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- Focal atresia of segmental bronchus
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- Typically affects left upper lobe apicoposterior segment
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- Recurrent infection in 20% of patients
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- CT: Tubular or branching opacity surrounded by hyperlucent lung due to air-trapping and oligemia
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- ## Helpful Clues for Less Common Diagnoses
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- **Bronchiectasis**
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- Cystic fibrosis
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- Autosomal recessive disorder that affects regulation of chloride transport
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- Recurrent infection, progressive bronchial wall injury
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- Diffuse bronchiectasis (upper lobe predominant); central and peripheral airways affected
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- Primary ciliary dyskinesia
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- Structural abnormality that affects ciliary motion
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- Bronchiectasis, sinusitis, infertility
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- Basilar predominant airway involvement
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- **Benign Airway Neoplasm**
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- Hamartoma
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- Endobronchial (1.4% of cases)
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- Fat &/or calcification in endobronchial lesion supports diagnosis
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- Lipoma
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- Endobronchial lipoma (0.1-0.5% of lung tumors)
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- Nonenhancing homogeneous fat attenuation lesion
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- **Malignant Airway Neoplasm**
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- Carcinoid tumor
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- Low-grade neuroendocrine neoplasm
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- Intrinsic calcification; may be eccentric
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- Marked contrast enhancement
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- Lung cancer
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- Centrally obstructing mass
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- Mucoid impaction uncommon
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- **Foreign Body**
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- Patients < 15 years of age (70%)
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- Most frequent location: Right lower lobe bronchus and bronchus intermedius
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- Adults: Chronic clinical course, recurrent pneumonia
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---
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title: "Finger-in-Glove Sign"
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docid: "81c5db2f-b8f6-4092-bcd2-ffb8aa3ab18a"
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breadcrumbs:
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- "Chest"
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- "Differential Diagnosis"
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- "Airways"
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- "General Imaging Patterns"
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- "Finger-in-Glove Sign"
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---
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# ESSENTIAL INFORMATION
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- ## Key Differential Diagnosis Issues
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- Finger-in-glove sign: Mucoid impaction with resultant dilated or impacted bronchi
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- Bronchial obstruction: Atresia, foreign body, neoplasm
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- Nonobstructive entities: Allergic bronchopulmonary aspergillosis, cystic fibrosis
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- Radiography/CT: Branching tubular opacities that typically radiate from hilum toward lung periphery
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- Differential diagnosis of bronchial branching tubular opacities
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- Arteriovenous malformation
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- Exhibits contrast enhancement
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- Demonstrates afferent and efferent vessels: Feeding artery(ies) and draining vein(s)
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- ## Helpful Clues for Common Diagnoses
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- **Allergic Bronchopulmonary Aspergillosis**
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- Immunologic disorder caused by hypersensitivity to*Aspergillus fumigatus*
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- Predisposing conditions: Asthma, cystic fibrosis
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- Laboratory findings: Positive aspergillus skin test, elevated IgE levels against *Aspergillus fumigatus*
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- Total IgE levels > 1,000 IU/mL
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- IgG antibodies against*A. fumigatus* in serum
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- Total eosinophil count > 500 cells/mL
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- Imaging: Branching tubular opacities, high attenuation on CT due to intrinsic calcium oxalate
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- **Congenital Bronchial Atresia**
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- Focal atresia of segmental bronchus
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- Typically affects left upper lobe apicoposterior segment
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- Recurrent infection in 20% of patients
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- CT: Tubular or branching opacity surrounded by hyperlucent lung due to air-trapping and oligemia
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- ## Helpful Clues for Less Common Diagnoses
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- **Bronchiectasis**
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- Cystic fibrosis
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- Autosomal recessive disorder that affects regulation of chloride transport
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- Recurrent infection, progressive bronchial wall injury
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- Diffuse bronchiectasis (upper lobe predominant); central and peripheral airways affected
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- Primary ciliary dyskinesia
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- Structural abnormality that affects ciliary motion
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- Bronchiectasis, sinusitis, infertility
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- Basilar predominant airway involvement
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- **Benign Airway Neoplasm**
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- Hamartoma
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- Endobronchial (1.4% of cases)
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- Fat &/or calcification in endobronchial lesion supports diagnosis
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- Lipoma
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- Endobronchial lipoma (0.1-0.5% of lung tumors)
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- Nonenhancing homogeneous fat attenuation lesion
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- **Malignant Airway Neoplasm**
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- Carcinoid tumor
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- Low-grade neuroendocrine neoplasm
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- Intrinsic calcification; may be eccentric
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- Marked contrast enhancement
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- Lung cancer
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- Centrally obstructing mass
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- Mucoid impaction uncommon
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- **Foreign Body**
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- Patients < 15 years of age (70%)
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- Most frequent location: Right lower lobe bronchus and bronchus intermedius
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- Adults: Chronic clinical course, recurrent pneumonia
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---
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title: "Tracheal Dilatation"
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docid: "25c1fd77-52ff-4a56-b5c4-6ee1335ba369"
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breadcrumbs:
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- "Chest"
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- "Differential Diagnosis"
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- "Airways"
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- "General Imaging Patterns"
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- "Tracheal Dilatation"
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---
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# ESSENTIAL INFORMATION
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- ## Key Differential Diagnosis Issues
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- Tracheal wall composed of several layers: Mucosa, submucosa, cartilage or muscle, and adventitia
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- Horseshoe-shaped bands of hyaline cartilage support anterior and lateral tracheal walls
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- Posterior tracheal wall lacks cartilage and is supported by band of smooth muscle
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- During expiration: Anterior bulging of posterior wall of intrathoracic trachea and ↓ of tracheal AP diameter by 32%
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- Tracheal dilatation
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- Women
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- Tracheal transverse diameter > 21 mm, sagittal diameter > 23 mm
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- Men
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- Tracheal transverse diameter > 25 mm, sagittal diameter > 27 mm
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- Tracheal index: Coronal diameter/sagittal diameter measured 1 cm above aortic arch
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- Normal index ~ 1
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- ## Helpful Clues for Common Diagnoses
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- **Upper Lobe Fibrosis**
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- Retraction of tracheobronchial walls
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- Tuberculosis
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- Sarcoidosis
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- Hypersensitivity pneumonitis
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- **Overdistention of Endotracheal Tube Cuff**
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- Endotracheal tube or tracheostomy cannula cuff should not result in tracheal wall bulging
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- Endotracheal cuff located 2 cm from distal end
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- Overinflation of balloon to 1.5x diameter of normal trachea is associated with tracheal injury
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- **Saber-Sheath Trachea**
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- ↓ in coronal diameter of intrathoracic trachea associated with ↑ in sagittal diameter
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- Associated with COPD (95%)
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- Likely related to abnormal intrathoracic pressure
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- **Tracheobronchomalacia**
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- Condition characterized by excessive airway collapsibility caused by weakness of airway walls due to softening or destruction of supporting cartilage
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- Tracheomalacia patients have dilated and flaccid airway
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- ↓ in cross-sectional area > 70% during expiration compared with inspiration is generally considered diagnostic
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- ## Helpful Clues for Less Common Diagnoses
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- **Tracheal Diverticulum**
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- Mucosal herniation through tracheal wall from ↑ intraluminal pressure
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- Right posterolateral tracheal wall near thoracic inlet
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- Between tracheal cartilaginous and muscular portions
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- Communication with tracheal lumen rarely identified
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- **Mounier-Kuhn Syndrome**
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- Atrophy of muscular and elastic tissues in walls of trachea and mainstem bronchi
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- More common in men
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- Tracheal diameter > 30 mm (81.2%)
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- Bronchiectasis (48.6-57.6%)
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- Tracheal wall corrugated due to mucosa herniating between tracheal rings
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