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Craniocervical Junction Acute Injury 89ec23bf-2ed4-4694-98a7-7064d22cbf16
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bee1f359-33fb-4cba-9e6b-ed1ca1842439 Jeffrey S. Ross, MD
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86b8c311-8667-4afd-9b2b-0c2036a02b8a Julia R. Crim, MD
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Spine a58ff524-e50c-41ce-8979-65b534939534 21 02/02/23 Craniocervical Junction Acute Injury Spine, Differential Diagnosis, Craniovertebral Junction, Anatomically Based Differentials, Craniocervical Junction Acute Injury Craniocervical Junction Acute Injury | STATdx Craniocervical Junction Acute Injury DDX
Spine
Differential Diagnosis
Craniovertebral Junction
Anatomically Based Differentials
Craniocervical Junction Acute Injury

title: "Craniocervical Junction Acute Injury" docid: "89ec23bf-2ed4-4694-98a7-7064d22cbf16" authors:

  • key: "bee1f359-33fb-4cba-9e6b-ed1ca1842439" value: "Jeffrey S. Ross, MD"
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  • name: "Craniocervical Junction Acute Injury" slug: "craniocervical-junction-acute-inju-" treeNodeId: null category: "Spine" documentVersionId: "a58ff524-e50c-41ce-8979-65b534939534" imageCount: 21 lastUpdated: "02/02/23" pageDescription: "Craniocervical Junction Acute Injury" pageKeywords: "Spine, Differential Diagnosis, Craniovertebral Junction, Anatomically Based Differentials, Craniocervical Junction Acute Injury" pageTitle: "Craniocervical Junction Acute Injury | STATdx" enhancedTitle: "Craniocervical Junction Acute Injury" type: "DDX" breadcrumbs:
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  • "Craniocervical Junction Acute Injury"

ESSENTIAL INFORMATION

  • Key Differential Diagnosis Issues

    • Coronal, sagittal CT reformations essential for full evaluation of injury
    • MR very useful to evaluate for ligament injuries, cord injury, disc herniations
    • CT angiogram equally accurate (and faster) than MR angiogram for vertebral dissection - Time is often of essence in these patients, who tend to have multiple injuries
  • Helpful Clues for Common Diagnoses

    • Occipital Condyle Fracture - CT best method of diagnosis - Symptoms and outcome determined by associated head injury - Cranial nerve deficits in 30%
    • Jefferson C1 Fracture - If combined displacement of lateral masses > 6.9 mm, unstable - High likelihood of other fractures: Spine, skull, pelvis, lower extremity
    • Odontoid C2 Fracture - Usually low-velocity injury in older adult - Type II most frequent
    • Chronic Injury Mimics - Os odontoideum - Chronic, nonunited odontoid fracture - Smooth corticated margins
    • Nontraumatic Mimics - Pseudosubluxation C2-C3 - Children < 10 years old; anterolisthesis may measure up to 4 mm
  • Helpful Clues for Less Common Diagnoses

    • Atlantoccipital Dislocation - High incidence of cord injury - Formerly usually fatal; now patients often survive to hospital
    • Atlantoaxial Dislocation - Normal atlantoaxial joint space < 3.4 mm in adults on CT
    • Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) - Occurs primarily in children - MR: Injuries to cord, ligaments, intervertebral discs, cartilaginous endplates - 2/3 of severe cervical injuries in children < 8 years are SCIWORA

Images

Selected Images

Coronal NECT shows a nondisplaced occipital condyle fracture  as well as a C4 articular pillar fracture , reflecting lateral flexion injury. Occipital Condyle Fracture Coronal NECT shows a nondisplaced occipital condyle fracture as well as a C4 articular pillar fracture , reflecting lateral flexion injury.

Coronal NECT shows a nondisplaced occipital condyle fracture  as well as a C4 articular pillar fracture , reflecting lateral flexion injury. Occipital Condyle Fracture Coronal NECT shows a nondisplaced occipital condyle fracture as well as a C4 articular pillar fracture , reflecting lateral flexion injury.

Axial CT shows a type 3 condyle fracture  rotated into the foramen magnum. Note the normal position of the right condyle . Occipital Condyle Fracture Axial CT shows a type 3 condyle fracture rotated into the foramen magnum. Note the normal position of the right condyle .

Axial bone CT shows multiple fractures of the C1 ring . Lateral displacement in this patient indicates rupture of the transverse ligament of dens and resultant instability. Jefferson C1 Fracture Axial bone CT shows multiple fractures of the C1 ring . Lateral displacement in this patient indicates rupture of the transverse ligament of dens and resultant instability.

Parasagittal CT shows a condyle fracture  that has maintained its relationship with the lateral mass of C1  despite the posterior displacement. Occipital Condyle Fracture Parasagittal CT shows a condyle fracture that has maintained its relationship with the lateral mass of C1 despite the posterior displacement.

Sagittal NECT shows a type 2 dens fracture  in an osteoporotic patient. Soft tissue swelling is mild. These fractures are commonly subtle on radiographs and best seen on lateral (not odontoid) view. If there is any question, perform CT. Odontoid C2 Fracture Sagittal NECT shows a type 2 dens fracture in an osteoporotic patient. Soft tissue swelling is mild. These fractures are commonly subtle on radiographs and best seen on lateral (not odontoid) view. If there is any question, perform CT.

Plain radiograph shows a fracture through the base of the odontoid , which is displaced posteriorly with slight extension. Odontoid C2 Fracture Plain radiograph shows a fracture through the base of the odontoid , which is displaced posteriorly with slight extension.

Sagittal bone CT shows a comminuted C2 body fracture with characteristic retropulsion of the posterior cortex . Additional burst fractures are commonly present elsewhere in the spine. Burst Fracture, C2 Sagittal bone CT shows a comminuted C2 body fracture with characteristic retropulsion of the posterior cortex . Additional burst fractures are commonly present elsewhere in the spine.

Sagittal T1WI MR shows a well-defined fracture line . MR is useful for defining soft tissue abnormalities but should not be relied upon for pure bony fracture identification. Odontoid C2 Fracture Sagittal T1WI MR shows a well-defined fracture line . MR is useful for defining soft tissue abnormalities but should not be relied upon for pure bony fracture identification.

Sagittal oblique 3D CT shows bilateral C2 pedicle fractures  without fracture of the vertebral body. Effendi classification uses the presence of disruption of the C2-C3 disc and facet joints as a measure of the severity of injury. Hangman's C2 Fracture Sagittal oblique 3D CT shows bilateral C2 pedicle fractures without fracture of the vertebral body. Effendi classification uses the presence of disruption of the C2-C3 disc and facet joints as a measure of the severity of injury.

3D CT reconstruction visualizes the markedly left rotated C1  with respect to the mildly rotated C2 . Findings are typical of a Fielding-Hawkins type I atlantoaxial rotatory fixation. Atlantoaxial Rotary Subluxation/Fixation 3D CT reconstruction visualizes the markedly left rotated C1 with respect to the mildly rotated C2 . Findings are typical of a Fielding-Hawkins type I atlantoaxial rotatory fixation.

Sagittal bone CT shows a chronic, nonunited dens fracture , so-called os odontoideum. This may be unstable, and flexion-extension views should be performed. Os Odontoideum Sagittal bone CT shows a chronic, nonunited dens fracture , so-called os odontoideum. This may be unstable, and flexion-extension views should be performed.

Axial bone CT shows anterior and posterior clefts  of C1. Smooth, corticated margins are signs distinguishing this from trauma. Craniovertebral Junction Variants Axial bone CT shows anterior and posterior clefts of C1. Smooth, corticated margins are signs distinguishing this from trauma.

Sagittal bone CT shows the anterior arch of C1 fused to the clivus  and posterior arch fused to C2 . Craniovertebral Junction Variants Sagittal bone CT shows the anterior arch of C1 fused to the clivus and posterior arch fused to C2 .

Parasagittal CT shows posterior displacement of the lateral mass of C1 with respect to the occipital condyle . The normal condyle would be closely applied to the lateral mass of C1. Atlantooccipital Dislocation Parasagittal CT shows posterior displacement of the lateral mass of C1 with respect to the occipital condyle . The normal condyle would be closely applied to the lateral mass of C1.

Sagittal CT shows widening of the basion-dental interval  and slight posterior displacement of the odontoid with respect to the foramen magnum  (i.e., abnormal Wackenheim clival line). Atlantooccipital Dislocation Sagittal CT shows widening of the basion-dental interval and slight posterior displacement of the odontoid with respect to the foramen magnum (i.e., abnormal Wackenheim clival line).

Parasagittal CT shows slight widening of both C0-C1  and C1-C2  articulations in this patient with both atlantooccipital and atlantoaxial subluxations. Atlantooccipital Dislocation Parasagittal CT shows slight widening of both C0-C1 and C1-C2 articulations in this patient with both atlantooccipital and atlantoaxial subluxations.

Sagittal STIR MR shows diffuse prevertebral high signal from edema   and a widened basion-dental interval . Note the disruption of the tectorial membrane . Atlantooccipital Dislocation Sagittal STIR MR shows diffuse prevertebral high signal from edema and a widened basion-dental interval . Note the disruption of the tectorial membrane .

Sagittal STIR MR shows abnormal hyperintensity within the C0-C1 and C1-C2 articulations  due to simultaneous atlantooccipital and atlantoaxial subluxations. The 2-level abnormality is important to identify since the posterior fusion will be extended more inferiorly. Atlantoaxial Dislocation Sagittal STIR MR shows abnormal hyperintensity within the C0-C1 and C1-C2 articulations due to simultaneous atlantooccipital and atlantoaxial subluxations. The 2-level abnormality is important to identify since the posterior fusion will be extended more inferiorly.

Coronal CT shows the disrupted spinal articulations at C1-C2 (atlantoaxial dissociation). There is widening of the atlantoodontoid articulation  and widening/dislocation of the lateral masses of C1 and C2 . Atlantoaxial Dislocation Coronal CT shows the disrupted spinal articulations at C1-C2 (atlantoaxial dissociation). There is widening of the atlantoodontoid articulation and widening/dislocation of the lateral masses of C1 and C2 .

Sagittal CT shows gross widening of the atlantoodontoid articulation . The ring of C1 has maintained position with respect to the foramen magnum , but C2 is displaced posteriorly . Atlantoaxial Dislocation Sagittal CT shows gross widening of the atlantoodontoid articulation . The ring of C1 has maintained position with respect to the foramen magnum , but C2 is displaced posteriorly .

Additional Images

Sagittal bone CT shows occipital condyle  widely separated from lateral mass of C1 , indicating longitudinal atlantooccipital dislocation. Dislocation may also be anterior or posterior in direction. Atlantooccipital Dislocation Sagittal bone CT shows occipital condyle widely separated from lateral mass of C1 , indicating longitudinal atlantooccipital dislocation. Dislocation may also be anterior or posterior in direction.