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---
title: "Cystic CPA Mass"
docid: "6c60db6d-8093-4df5-8cbb-c6f6570ae167"
authors:
- key: "07a2c087-6202-49e7-870b-7aa162d18f06"
value: "Bronwyn E. Hamilton, MD"
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name: "Head and Neck"
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name: "Differential Diagnosis"
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slug: "cpa-iac-and-posterior-fossa"
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lastUpdated: "02/09/24"
pageDescription: "Cystic CPA Mass"
pageKeywords: "Head and Neck, Differential Diagnosis, CPA-IAC and Posterior Fossa, Generic Imaging Patterns, Cystic CPA Mass"
pageTitle: "Cystic CPA Mass | STATdx"
enhancedTitle: "Cystic CPA Mass"
type: "DDX"
references: true
breadcrumbs:
- "Head and Neck"
- "Differential Diagnosis"
- "CPA-IAC and Posterior Fossa"
- "Generic Imaging Patterns"
- "Cystic CPA Mass"
---
# ESSENTIAL INFORMATION
- ## Key Differential Diagnosis Issues
- This differential diagnosis is constructed around lesions of cerebellopontine angle (CPA) that may have "cystic" imaging features
- Typically cystic lesions: Epidermoid, arachnoid, & neurenteric cysts; neurocysticercosis & large endolymphatic sac anomaly
- Many solid CPA tumors may have either intramural cysts, necrosis, or extramural cysts as typical or variant MR imaging manifestation
- Schwannoma: Vestibular, facial nerve, trigeminal, or jugular foramen schwannoma with intramural or extramural cysts can all be found in CPA area
- Hemangioblastoma: Cerebellar cystic & solid tumor that may project into CPA cistern
- Endolymphatic sac tumor: CPA involved if large
- Cystic meningioma
- Idealized imaging protocol in evaluating cystic CPA masses
- T1 C+ fat-saturated MR is gold standard
- Contrast helps differentiate solid from cystic components of tumors, such as vestibular or facial nerve schwannoma & hemangioblastoma
- DWI for possible epidermoid cyst (restricted diffusion)
- T2 thin-section, high-resolution MR
- Also sorts out solid and cystic components of lesions
- Helps with cranial nerve & vascular anatomy
- ## Helpful Clues for Common Diagnoses
- **Epidermoid Cyst**
- Key facts
- Definition: Congenital rest of epithelial tissue in CPA
- Imaging findings
- Insinuating or scalloping brainstem margin
- T1 MR: Iso- to slightly hyperintense relative to CSF
- T1 C+ MR: Typically nonenhancing cyst; may be hard to see
- Minimal marginal cyst enhancement in 25%
- Soft tissue enhancement present in rare cases of malignant degeneration to squamous cell carcinoma; PET avidity can help confirm suspicion
- T2 MR: High-signal, well-circumscribed CPA mass
- FLAIR: Lack of complete fluid suppression
- DWI: Restricted diffusion (high signal) makes diagnosis
- **Arachnoid Cyst**
- Key facts
- Definition: Congenital lesion resulting from failure of embryonic meninges to merge results in cyst between split arachnoid membrane
- Imaging findings
- Fills cistern with rounded margins
- T1 C+ MR: No enhancement
- FLAIR: Lesion attenuates (black like CSF)
- DWI: Isointense to CSF (no restriction)
- ## Helpful Clues for Less Common Diagnoses
- **Vestibular Schwannoma W****ith Intramural Cyst(s)**
- Key facts
- Definition: Vestibular schwannoma may have either intramural or extramural cysts associated
- Imaging findings
- Solid CPA-IAC mass with intramural cysts
- Bone CT: Larger lesions flare medial IAC component
- T1 C+ MR: Enhancing solid tumor component ± intramural cysts (common) ± extramural cyst (rare)
- Microhemorrhages on T2* GRE or SWI favor schwannoma over meningioma
- **Hemangioblastoma**
- Key facts
- Definition: Benign tumor composed of stromal cells in small blood vessels of CNS
- Adult with intraaxial posterior fossa mass abutting pia
- Associated with von Hippel Lindau (VHL) in 25-40%
- Supratentorial hemangioblastomas more likely VHL related
- Imaging findings
- Cerebellar cystic & solid tumor
- T1 C+ MR: 60% of tumors with solid enhancing & cystic components (40% solid only)
- **Large Endolymphatic Sac Anomaly (IP-II)**
- Key facts
- Bilateral congenital sensorineural hearing loss that appears in child with cascading hearing loss pattern
- Most common congenital imaging abnormality
- Recommendation to avoid contact sports
- Imaging findings
- Bone CT: Enlarged bony vestibular aqueduct
- T2 high-resolution MR: Enlarged endolymphatic sac & duct + mild cochlear malformation (modiolar deficiency, deficient apical septation, & scalar chamber asymmetry)
- **Neurocysticercosis**
- Key facts
- Definition: Intracranial infection caused by pork tapeworm (*Taenia solium*)
- Imaging findings
- Cysts with "dots" inside
- Appearance varies with stage
- T1 C+ MR: Cysts with enhancing thin or thick wall
- May be associated with hydrocephalus
- ## Helpful Clues for Rare Diagnoses
- **Vestibular Schwannoma W****ith Extramural Cyst**
- Key facts
- Vestibular schwannoma with extramural cyst
- Cyst may be "trapped CSF" or actual arachnoid cyst
- Neurootologists call extramural cyst "herald cyst"
- Imaging findings
- CPA-IAC mass with extramural cyst
- Bone CT: Large lesions flare IAC medial component
- T1 C+ MR: Enhancing solid tumor component ± extramural cyst
- Microhemorrhages on T2* GRE or SWI favor schwannoma over meningioma
- **Facial Nerve Schwannoma in CPA-IAC W****ith Cyst**
- Key facts
- Rare CPA-IAC mass with labyrinthine tail involving labyrinthine segment of facial nerve canal
- Often presents with hearing loss before facial nerve symptoms
- Imaging findings
- Bone CT: Labyrinthine segment of facial nerve may be enlarged
- T1 C+ MR: Enhancing tubular mass in CPA-IAC & labyrinthine segment of facial nerve; intramural or extramural cyst visible
- **Schwannoma, Trigeminal, Skull Base**
- Key facts
- Most common presentation is ipsilateral facial pain
- Imaging findings
- CPA cystic enhancing mass with tail extending toward or into Meckel cave is characteristic
- Look for denervation of masticator space muscles
- **Neurenteric****C****yst**
- Key facts
- Arises at time of notochordal development during transitory existence of neurenteric canal
- Benign endodermal lesion of CNS
- Often presents as incidental rounded to ovoid mass in prepontine cistern
- Imaging findings
- MR shows intermediate- to high-signal T1 prepontine "cystic" mass
- **Jugular Foramen Schwannoma W****ith Intramural Cyst**
- Key facts
- Presents with mixture of 9-12 cranial neuropathy
- Imaging findings
- Bone CT: Enlarged, sharply marginated jugular foramen
- T1 MR: Iso-g to hyperintense compared to CSF
- T1 C+ MR: Enhancing mass with intramural cysts arising from jugular foramen
- Intramural cysts in 25% of jugular foramen schwannomas
- Other MR findings: Mass projects superomedially into CPA cistern, often with brainstem compression
- **Cystic Metastasis in CPA**
- Key facts
- Usually in patients with known primary cancer
- Imaging findings
- T1 C+ MR: Enhancing mass with cystic component may mimic schwannoma or cystic meningioma
- Likely to exhibit rapid growth pattern and more symptoms, such as facial nerve palsy, than benign tumors like schwannoma
- **Endolymphatic Sac Tumor**
- Key facts
- Sporadic or associated with VHL
- Bilateral tumors &/or concurrent hemangioblastoma indicates VHL
- Imaging findings
- Bone CT: Permeative destruction of posterior petrous temporal bone centered at vestibular aqueduct
- T1 MR: Hyperintense foci due to internal hemorrhage are characteristic
- T1 C+ MR: Partly cystic, heterogenous enhancing mass
- DOTATATE scan may show mild uptake due to somatostatin receptor type 2A expression in tumor vasculature not tumor cells
- **Meningioma, Cystic**
- T1 C+ MR: Rare, heterogeneous, partly cystic enhancing mass
- Rare meningioma variant that mimics schwannoma; most are clear cell subtype
## References
# Selected References
1. [Ali NE et al: Natural history of cystic vestibular schwannomas. Ann Otol Rhinol Laryngol. 132(7):795-9, 2023](http://www.ncbi.nlm.nih.gov/pubmed/?term=35993287%5Bpmid%5D)
1. [Adachi S et al: Unusual imaging characteristics of cystic meningioma in cerebellopontine angle. Neuroradiol J. 35(6):777-9, 2022](http://www.ncbi.nlm.nih.gov/pubmed/?term=35503008%5Bpmid%5D)
1. [Geng Y et al: Endolymphatic sac tumour: exploring the role of CT and MRI features in the diagnosis of 22 cases. Clin Radiol. 77(8):e592-8, 2022](http://www.ncbi.nlm.nih.gov/pubmed/?term=35643739%5Bpmid%5D)
1. [Talukdar R et al: Endolymphatic sac tumor: single-institution series of seven cases with updated review of literature. Eur Arch Otorhinolaryngol. 279(5):2591-8, 2022](http://www.ncbi.nlm.nih.gov/pubmed/?term=34410472%5Bpmid%5D)
1. [Parlak S et al: 3 Tesla MR imaging of the large endolymphatic duct and sac anomaly with audiological correlation. Eur J Radiol. 145:110064, 2021](http://www.ncbi.nlm.nih.gov/pubmed/?term=34839211%5Bpmid%5D)
1. [Saigal G et al: Utility of microhemorrhage as a diagnostic tool in distinguishing vestibular schwannomas from other cerebellopontine angle (CPA) Tumors. Indian J Otolaryngol Head Neck Surg. 73(3):321-6, 2021](http://www.ncbi.nlm.nih.gov/pubmed/?term=34471620%5Bpmid%5D)
1. [Lou R et al: 68Ga-DOTATATE uptake in an endolymphatic sac tumor: radiologic-pathologic correlation. Clin Nucl Med. 45(7):563-5, 2020](http://www.ncbi.nlm.nih.gov/pubmed/?term=32433163%5Bpmid%5D)
1. [Connor SEJ et al: Is CT or MRI the optimal imaging investigation for the diagnosis of large vestibular aqueduct syndrome and large endolymphatic sac anomaly? Eur Arch Otorhinolaryngol. 276(3):693-702, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=30635710%5Bpmid%5D)
1. [Eliezer M et al: Clinical and radiological characteristics of malignant tumors located to the cerebellopontine angle and/or internal acoustic meatus. Otol Neurotol. 40(9):1237-45, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=31469787%5Bpmid%5D)
1. [Le H et al: Clinicoradiologic characteristics of endolymphatic sac tumors. Eur Arch Otorhinolaryngol. 276(10):2705-14, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=31197530%5Bpmid%5D)
1. [Touska P et al: Temporal bone tumors: an imaging update. Neuroimaging Clin N Am. 29(1):145-72, 2019](http://www.ncbi.nlm.nih.gov/pubmed/?term=30466638%5Bpmid%5D)
1. [Schnack DT et al: Sporadic endolymphatic sac tumor-a very rare cause of hearing loss, tinnitus, and dizziness. J Int Adv Otol. 13(2):289-91, 2017](http://www.ncbi.nlm.nih.gov/pubmed/?term=28716765%5Bpmid%5D)
1. [Agarwal A: Intracranial trigeminal schwannoma. Neuroradiol J. 28(1):36-41, 2015](http://www.ncbi.nlm.nih.gov/pubmed/?term=25924170%5Bpmid%5D)
1. [Dispenza F et al: Imaging of vestibular schwannoma with prevalent cystic component: cystic vestibular schwannoma. Otol Neurotol. 30(5):681-2, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=18716565%5Bpmid%5D)
1. [Piccirillo E et al: Cystic vestibular schwannoma: classification, management, and facial nerve outcomes. Otol Neurotol. 30(6):826-34, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=19704364%5Bpmid%5D)
1. [Zhang L et al: Trigeminal schwannomas: a report of 42 cases and review of the relevant surgical approaches. Clin Neurol Neurosurg. 111(3):261-9, 2009](http://www.ncbi.nlm.nih.gov/pubmed/?term=19081670%5Bpmid%5D)
1. [Bonneville F et al: Imaging of cerebellopontine angle lesions: an update. Part 1: enhancing extra-axial lesions. Eur Radiol. 17(10):2472-82, 2007](http://www.ncbi.nlm.nih.gov/pubmed/?term=17562049%5Bpmid%5D)
1. [Bonneville F et al: Imaging of cerebellopontine angle lesions: an update. Part 2: intra-axial lesions, skull base lesions that may invade the CPA region, and non-enhancing extra-axial lesions. Eur Radiol. 17(11):2908-20, 2007](http://www.ncbi.nlm.nih.gov/pubmed/?term=17569053%5Bpmid%5D)
1. [Kiliçkesmez O: Endolymphatic sac tumor in a patient with von Hippel-Lindau disease: MR imaging findings. Diagn Interv Radiol. 12(1):14-6, 2006](http://www.ncbi.nlm.nih.gov/pubmed/?term=16538578%5Bpmid%5D)
1. [Patel NP et al: The radiologic diagnosis of endolymphatic sac tumors. Laryngoscope. 116(1):40-6, 2006](http://www.ncbi.nlm.nih.gov/pubmed/?term=16481807%5Bpmid%5D)
1. [Preece MT et al: Intracranial neurenteric cysts: imaging and pathology spectrum. AJNR Am J Neuroradiol. 27(6):1211-6, 2006](http://www.ncbi.nlm.nih.gov/pubmed/?term=16775266%5Bpmid%5D)
1. [Nelson MD Jr et al: A different approach to cysts of the posterior fossa. Pediatr Radiol. 34(9):720-32, 2004](http://www.ncbi.nlm.nih.gov/pubmed/?term=15316692%5Bpmid%5D)
1. [Bonneville F et al: Unusual lesions of the cerebellopontine angle: a segmental approach. Radiographics. 21(2):419-38, 2001](http://www.ncbi.nlm.nih.gov/pubmed/?term=11259705%5Bpmid%5D)
1. [Davidson HC et al: MR evaluation of vestibulocochlear anomalies associated with large endolymphatic duct and sac. AJNR Am J Neuroradiol. 20(8):1435-41, 1999](http://www.ncbi.nlm.nih.gov/pubmed/?term=10512225%5Bpmid%5D)
1. [Koeller KK et al: Congenital cystic masses of the neck: radiologic-pathologic correlation. Radiographics. 19(1):121-46; quiz 152-3, 1999](http://www.ncbi.nlm.nih.gov/pubmed/?term=9925396%5Bpmid%5D)
1. [Lau KY et al: MRI demonstration of subarachnoid neurocysticercosis simulating metastatic disease. Neuroradiology. 40(11):724-6, 1998](http://www.ncbi.nlm.nih.gov/pubmed/?term=9860122%5Bpmid%5D)
1. [Mukherji SK et al: Papillary endolymphatic sac tumors: CT, MR imaging, and angiographic findings in 20 patients. Radiology. 202(3):801-8, 1997](http://www.ncbi.nlm.nih.gov/pubmed/?term=9051037%5Bpmid%5D)
1. [Tong KA et al: Large vestibular aqueduct syndrome: a genetic disease? AJR Am J Roentgenol. 168(4):1097-101, 1997](http://www.ncbi.nlm.nih.gov/pubmed/?term=9124122%5Bpmid%5D)
1. [Friedman DP et al: Vascular neoplasms and malformations, ischemia, and hemorrhage affecting the spinal cord: MR imaging findings. AJR Am J Roentgenol. 162(3):685-92, 1994](http://www.ncbi.nlm.nih.gov/pubmed/?term=8109522%5Bpmid%5D)
1. [Kollias SS et al: Cystic malformations of the posterior fossa: differential diagnosis clarified through embryologic analysis. Radiographics. 13(6):1211-31, 1993](http://www.ncbi.nlm.nih.gov/pubmed/?term=8031352%5Bpmid%5D)
1. [Smirniotopoulos JG et al: Cerebellopontine angle masses: radiologic-pathologic correlation. Radiographics. 13(5):1131-47, 1993](http://www.ncbi.nlm.nih.gov/pubmed/?term=8210595%5Bpmid%5D)
## Images
### Selected Images
![Axial T1 C+ MR reveals a low signal intensity, nonenhancing epidermoid cyst that insinuates into the foramen of Luschka <img src='img/arrows/WS.png'/> and along the right cerebellar hemisphere <img src='img/arrows/WO.png'/>. DWI MR sequence would show restricted diffusion. FLAIR would show lack of complete fluid suppression.](images/app.statdx.com_image_thumbnail_9c20ab07-d905-4fe9-825e-f669857ed535_annotated_true_size_900_quality_90_e351d8febf9476ec73cfce123b434851a06e0145.jpg)
**Epidermoid Cyst**
*Axial T1 C+ MR reveals a low signal intensity, nonenhancing epidermoid cyst that insinuates into the foramen of Luschka <img src='img/arrows/WS.png'/> and along the right cerebellar hemisphere <img src='img/arrows/WO.png'/>. DWI MR sequence would show restricted diffusion. FLAIR would show lack of complete fluid suppression.*
![Axial T1 C+ MR reveals a low signal intensity, nonenhancing epidermoid cyst that insinuates into the foramen of Luschka <img src='img/arrows/WS.png'/> and along the right cerebellar hemisphere <img src='img/arrows/WO.png'/>. DWI MR sequence would show restricted diffusion. FLAIR would show lack of complete fluid suppression.](images/app.statdx.com_image_thumbnail_9c20ab07-d905-4fe9-825e-f669857ed535_size_174_quality_85_6e8cf09baa5ca522a92db8265f55ecb0c30a7537.jpg)
**Epidermoid Cyst**
*Axial T1 C+ MR reveals a low signal intensity, nonenhancing epidermoid cyst that insinuates into the foramen of Luschka <img src='img/arrows/WS.png'/> and along the right cerebellar hemisphere <img src='img/arrows/WO.png'/>. DWI MR sequence would show restricted diffusion. FLAIR would show lack of complete fluid suppression.*
![Axial T1 C+ FS MR demonstrates a right cerebellopontine angle (CPA) cistern arachnoid cyst <img src='img/arrows/WS.png'/> displacing the proximal facial and vestibulocochlear nerves anteriorly <img src='img/arrows/WO.png'/>.](images/app.statdx.com_image_thumbnail_3c4ccfba-a118-420e-b3fe-9c8060624960_annotated_true_size_900_quality_90_196626e9d948a819f4d28a8d5c2cce6415f1af6a.jpg)
**Arachnoid Cyst**
*Axial T1 C+ FS MR demonstrates a right cerebellopontine angle (CPA) cistern arachnoid cyst <img src='img/arrows/WS.png'/> displacing the proximal facial and vestibulocochlear nerves anteriorly <img src='img/arrows/WO.png'/>.*
![Axial T1 C+ MR shows a large enhancing vestibular schwannoma projecting from the internal auditory canal (IAC) <img src='img/arrows/WS.png'/> into the CPA cistern. The tumor has a large intramural cyst <img src='img/arrows/WO.png'/> that compresses the brainstem and cerebellum.](images/app.statdx.com_image_thumbnail_7bf8f980-b96a-4a73-8723-f4065bec6928_annotated_true_size_900_quality_90_4865caae16e5a0b266a793cefc08bfe19e56e74c.jpg)
**Vestibular Schwannoma With Intramural Cyst(s)**
*Axial T1 C+ MR shows a large enhancing vestibular schwannoma projecting from the internal auditory canal (IAC) <img src='img/arrows/WS.png'/> into the CPA cistern. The tumor has a large intramural cyst <img src='img/arrows/WO.png'/> that compresses the brainstem and cerebellum.*
![Axial T2 MR shows a heterogeneous CPA mass <img src='img/arrows/WS.png'/> extending into the left internal auditory canal. Note numerous large intramural tumor cysts <img src='img/arrows/WC.png'/>.](images/app.statdx.com_image_thumbnail_c0eea3bd-14f3-436b-bd9e-2818f22f0815_annotated_true_size_900_quality_90_a453d30064cbb01de279d0559dfd07ad5bee5732.jpg)
**Vestibular Schwannoma With Intramural Cyst(s)**
*Axial T2 MR shows a heterogeneous CPA mass <img src='img/arrows/WS.png'/> extending into the left internal auditory canal. Note numerous large intramural tumor cysts <img src='img/arrows/WC.png'/>.*
![Axial T1 C+ FS MR shows a superficial, intracerebellar mixed cystic-solid hemangioblastoma projecting into the left CPA cistern area. The solid nodule <img src='img/arrows/WS.png'/> is avidly enhancing.](images/app.statdx.com_image_thumbnail_d1e63db5-1084-4898-b8fa-f79e0f3ca30a_annotated_true_size_900_quality_90_2bab8529cee1a7b2563c33080b40f35460f8ca1b.jpg)
**Hemangioblastoma**
*Axial T1 C+ FS MR shows a superficial, intracerebellar mixed cystic-solid hemangioblastoma projecting into the left CPA cistern area. The solid nodule <img src='img/arrows/WS.png'/> is avidly enhancing.*
![Axial T2WI MR shows a large endolymphatic sac <img src='img/arrows/WS.png'/> within the posterior wall of the temporal bone. CT (not shown) would reveal a large bony vestibular aqueduct in this patient with large endolymphatic sac anomaly.](images/app.statdx.com_image_thumbnail_b37a1a80-0202-4d7e-ae55-3e9bda0fc7ff_annotated_true_size_900_quality_90_939d6d673c5ef8efc2b3757675d3afc0389b853e.jpg)
**Large Endolymphatic Sac Anomaly (IP-II)**
*Axial T2WI MR shows a large endolymphatic sac <img src='img/arrows/WS.png'/> within the posterior wall of the temporal bone. CT (not shown) would reveal a large bony vestibular aqueduct in this patient with large endolymphatic sac anomaly.*
![Axial T1 C+ FS MR demonstrates a cystic mass in the right CPA cistern with a peripherally enhancing wall <img src='img/arrows/WS.png'/>. Adjacent enhancing, thickened meninges <img src='img/arrows/WO.png'/> are also seen.](images/app.statdx.com_image_thumbnail_b44f5a1f-4fb3-4472-b46b-f696341e792a_annotated_true_size_900_quality_90_8b1339b20b8eeec3c1fb2431e3a1207e8b4467c2.jpg)
**Neurocysticercosis**
*Axial T1 C+ FS MR demonstrates a cystic mass in the right CPA cistern with a peripherally enhancing wall <img src='img/arrows/WS.png'/>. Adjacent enhancing, thickened meninges <img src='img/arrows/WO.png'/> are also seen.*
![Axial T2WI MR shows a vestibular schwannoma <img src='img/arrows/WS.png'/> projecting from the IAC into the CPA cistern. An associated (extramural) arachnoid cyst is visible <img src='img/arrows/WO.png'/> compressing the brainstem and 4th ventricle <img src='img/arrows/WC.png'/>.](images/app.statdx.com_image_thumbnail_6ce94b8c-5228-4e64-ba8c-73a07f250d9e_annotated_true_size_900_quality_90_054cf049744f0a94edf30b6a0b7dec78fd873573.jpg)
**Vestibular Schwannoma With Extramural Cyst**
*Axial T2WI MR shows a vestibular schwannoma <img src='img/arrows/WS.png'/> projecting from the IAC into the CPA cistern. An associated (extramural) arachnoid cyst is visible <img src='img/arrows/WO.png'/> compressing the brainstem and 4th ventricle <img src='img/arrows/WC.png'/>.*
![Axial T1 C+ MR reveals an enhancing CPA mass <img src='img/arrows/WS.png'/>, with intramural cysts, which projected into the IAC but did not involve the labyrinthine segment. Note atrophy of the right platysma muscle <img src='img/arrows/BS.png'/> from CNVII denervation.](images/app.statdx.com_image_thumbnail_fd005ccd-437a-4a14-9656-afa375f84039_annotated_true_size_900_quality_90_ed15f34e2656f0d3eb999951c956965f618988d6.jpg)
**Facial Nerve Schwannoma in CPA-IAC With Cyst**
*Axial T1 C+ MR reveals an enhancing CPA mass <img src='img/arrows/WS.png'/>, with intramural cysts, which projected into the IAC but did not involve the labyrinthine segment. Note atrophy of the right platysma muscle <img src='img/arrows/BS.png'/> from CNVII denervation.*
![Axial T1 C+ MR demonstrates a large CPA cystic mass &quot;pointing&quot; toward the Meckel cave <img src='img/arrows/WS.png'/>, providing a clue to the origin of this mass. Note chronic denervation changes of volume loss and fatty infiltration in the left suprazygomatic masticator space <img src='img/arrows/WO.png'/> compared to the right <img src='img/arrows/WC.png'/>, partly seen here.](images/app.statdx.com_image_thumbnail_1ab17495-4701-4a87-9d4a-875ce4753c55_annotated_true_size_900_quality_90_e86c6a1ba3b74a7241f2fc52e98f0ef87625e4fd.jpg)
**Schwannoma, Trigeminal, Skull Base**
*Axial T1 C+ MR demonstrates a large CPA cystic mass &quot;pointing&quot; toward the Meckel cave <img src='img/arrows/WS.png'/>, providing a clue to the origin of this mass. Note chronic denervation changes of volume loss and fatty infiltration in the left suprazygomatic masticator space <img src='img/arrows/WO.png'/> compared to the right <img src='img/arrows/WC.png'/>, partly seen here.*
![Axial T1WI MR shows a small mass anterior to the pontomedullary junction <img src='img/arrows/WS.png'/>. The neurenteric cyst is well delineated, demonstrating nearly isointense signal to brain, and does not enhance significantly.](images/app.statdx.com_image_thumbnail_a91eb077-bbb8-4541-aadd-8d6b97771d71_annotated_true_size_900_quality_90_e3d2f496364c8a8dd9faf7da8b733ec9a48edf5d.jpg)
**Neurenteric Cyst**
*Axial T1WI MR shows a small mass anterior to the pontomedullary junction <img src='img/arrows/WS.png'/>. The neurenteric cyst is well delineated, demonstrating nearly isointense signal to brain, and does not enhance significantly.*
![Axial T2 FS MR reveals a large, sharply marginated lesion expanding the left jugular foramen <img src='img/arrows/WO.png'/>. The high-signal mass projects medially into the low CPA cistern where it compresses the brainstem <img src='img/arrows/WS.png'/>.](images/app.statdx.com_image_thumbnail_e02d8050-4c8c-47ab-9dc6-72fb657fc755_annotated_true_size_900_quality_90_84e1aec7a076f0c6e074fbaae5e14193c96e08d3.jpg)
**Jugular Foramen Schwannoma With Intramural Cyst**
*Axial T2 FS MR reveals a large, sharply marginated lesion expanding the left jugular foramen <img src='img/arrows/WO.png'/>. The high-signal mass projects medially into the low CPA cistern where it compresses the brainstem <img src='img/arrows/WS.png'/>.*
![Parasagittal T1 C+ FS MR shows a heterogeneous, cystic enhancing mass <img src='img/arrows/WC.png'/> in the right CPA <img src='img/arrows/WS.png'/>. Adjacent brain edema is noted <img src='img/arrows/WO.png'/>. Although the mass might mimic a cystic schwannoma, the presence of a 2nd enhancing mass and a clinical history of lung cancer helps establish diagnosis of metastasis.](images/app.statdx.com_image_thumbnail_5b3cba8d-233b-4c26-bf69-1bf1724ec332_annotated_true_size_900_quality_90_5e5c0f26dd9bc5d45d0b3e88a6b40564905cdbd5.jpg)
**Cystic Metastasis in CPA**
*Parasagittal T1 C+ FS MR shows a heterogeneous, cystic enhancing mass <img src='img/arrows/WC.png'/> in the right CPA <img src='img/arrows/WS.png'/>. Adjacent brain edema is noted <img src='img/arrows/WO.png'/>. Although the mass might mimic a cystic schwannoma, the presence of a 2nd enhancing mass and a clinical history of lung cancer helps establish diagnosis of metastasis.*
![Axial high-resolution T2 MR shows a heterogeneous cystic CPA mass <img src='img/arrows/WS.png'/>. The key to diagnosis is identifying the mass origin from the posterior temporal bone in the expected location of the endolymphatic sac.](images/app.statdx.com_image_thumbnail_c4086a2f-86ac-45ec-8b77-0450dd7a3253_annotated_true_size_900_quality_90_84105a86bfffb5992b08be1debd3af8f6940dc25.jpg)
**Endolymphatic Sac Tumor**
*Axial high-resolution T2 MR shows a heterogeneous cystic CPA mass <img src='img/arrows/WS.png'/>. The key to diagnosis is identifying the mass origin from the posterior temporal bone in the expected location of the endolymphatic sac.*
### Additional Images
![Axial T1 C+ MR shows an atypical heterogeneously enhancing left vestibular schwannoma <img src='img/arrows/WC.png'/> with an associated arachnoid cyst <img src='img/arrows/WS.png'/>.](images/app.statdx.com_image_thumbnail_9f150021-4d87-49a7-925e-4ea3b64654b4_annotated_true_size_900_quality_90_8a9e7d3d2ed808245de9fd1ef4ad27165926f6da.jpg)
**Vestibular Schwannoma With Extramural Cyst**
*Axial T1 C+ MR shows an atypical heterogeneously enhancing left vestibular schwannoma <img src='img/arrows/WC.png'/> with an associated arachnoid cyst <img src='img/arrows/WS.png'/>.*
![Coronal T1 C+ MR shows variant MR case of a jugular foramen schwannoma with intramural cyst <img src='img/arrows/WO.png'/> and very large cisternal component. The jugular foramen connection is seen on the next image.](images/app.statdx.com_image_thumbnail_24ab3e04-2e79-4dae-8c22-8c416a4660a1_annotated_true_size_900_quality_90_df237998eb576c906901bdfb971e6c95f4d91046.jpg)
**Jugular Foramen Schwannoma With Intramural Cyst**
*Coronal T1 C+ MR shows variant MR case of a jugular foramen schwannoma with intramural cyst <img src='img/arrows/WO.png'/> and very large cisternal component. The jugular foramen connection is seen on the next image.*
![Coronal T1 C+ MR reveals an enhancing schwannoma in the jugular foramen <img src='img/arrows/WS.png'/>. The tumor projects superomedially to fill the CPA cistern <img src='img/arrows/WO.png'/> and compress the brainstem.](images/app.statdx.com_image_thumbnail_10f067d8-6bbf-4dfc-8fb6-a6519378d65e_annotated_true_size_900_quality_90_9dbda4d9250e0a170600d7abb1287a092d1ebdc2.jpg)
**Jugular Foramen Schwannoma With Intramural Cyst**
*Coronal T1 C+ MR reveals an enhancing schwannoma in the jugular foramen <img src='img/arrows/WS.png'/>. The tumor projects superomedially to fill the CPA cistern <img src='img/arrows/WO.png'/> and compress the brainstem.*
![Axial T1 C+ MR in a patient presenting with left facial pain demonstrates a peripherally enhancing cystic mass in the left CPA with a vector of spread extending towards Meckel cave <img src='img/arrows/WS.png'/>, that was the clue to its origin.](images/app.statdx.com_image_thumbnail_8e1b3910-0e46-4a50-b25b-a246b6075585_annotated_true_size_900_quality_90_aac5b46dd4eb5e66d40e9bfdf3867afadd041967.jpg)
**Schwannoma, Trigeminal, Skull Base**
*Axial T1 C+ MR in a patient presenting with left facial pain demonstrates a peripherally enhancing cystic mass in the left CPA with a vector of spread extending towards Meckel cave <img src='img/arrows/WS.png'/>, that was the clue to its origin.*
![Coronal T1 C+ FS MR shows multiple cysts in the right CPA cistern <img src='img/arrows/WS.png'/> causing mass effect on the brainstem. Secondary hydrocephalus is present.](images/app.statdx.com_image_thumbnail_325f707f-6cd9-4ff6-b3f4-1afb2531d896_annotated_true_size_900_quality_90_5df80fbfd269508d2e9dbf873fb1f7014a21a8ab.jpg)
**Neurocysticercosis**
*Coronal T1 C+ FS MR shows multiple cysts in the right CPA cistern <img src='img/arrows/WS.png'/> causing mass effect on the brainstem. Secondary hydrocephalus is present.*
![Axial T2WI MR reveals an intracerebellar high signal hemangioblastoma <img src='img/arrows/WS.png'/> projecting into the CPA cistern area. Contrast is required to define enhancing nodule if present.](images/app.statdx.com_image_thumbnail_ab3c32c2-0d27-4ff0-9624-ee4d210b4639_annotated_true_size_900_quality_90_bd21cbeceb2e3e67412b922072d0f0ce9e48cefe.jpg)
**Hemangioblastoma**
*Axial T2WI MR reveals an intracerebellar high signal hemangioblastoma <img src='img/arrows/WS.png'/> projecting into the CPA cistern area. Contrast is required to define enhancing nodule if present.*
![Axial T1 C+ MR demonstrates an ovoid enhancing mass in the low CPA cistern <img src='img/arrows/WS.png'/>. Multiple intramural cysts suggest the diagnosis of schwannoma. Extension into the jugular foramen <img src='img/arrows/WO.png'/> is evident.](images/app.statdx.com_image_thumbnail_d7deb934-06d4-420e-94e5-31ffeeb65acf_annotated_true_size_900_quality_90_33f2136141742fa30e085373936a82852b2ed232.jpg)
**Jugular Foramen Schwannoma With Intramural Cyst**
*Axial T1 C+ MR demonstrates an ovoid enhancing mass in the low CPA cistern <img src='img/arrows/WS.png'/>. Multiple intramural cysts suggest the diagnosis of schwannoma. Extension into the jugular foramen <img src='img/arrows/WO.png'/> is evident.*
![Axial T1 C+ MR shows nodular soft tissue enhancement <img src='img/arrows/WO.png'/> along the margins of a cystic prepontine and left CPA epidermoid cyst <img src='img/arrows/WS.png'/>, due to a rare complication: Malignant degeneration into squamous cell carcinoma.](images/app.statdx.com_image_thumbnail_35f1691e-62c9-498c-b7cf-91f688ef64bd_annotated_true_size_900_quality_90_76f27969c2043b645695c0c222f5b2eda0358039.jpg)
**Epidermoid Cyst**
*Axial T1 C+ MR shows nodular soft tissue enhancement <img src='img/arrows/WO.png'/> along the margins of a cystic prepontine and left CPA epidermoid cyst <img src='img/arrows/WS.png'/>, due to a rare complication: Malignant degeneration into squamous cell carcinoma.*
![Axial T1 C+ MR shows a partly cystic, partly solid mass in the right CPA <img src='img/arrows/WS.png'/> and posterior Meckel cave <img src='img/arrows/WC.png'/>. Biopsy supported meningioma, which rarely may have cystic morphologies that mimic schwannoma.](images/app.statdx.com_image_thumbnail_3a0efbd0-7cbc-459a-9138-2b8124db1709_annotated_true_size_900_quality_90_8ebabac71d4ead80a517b96323940e2adbef86ea.jpg)
**Meningioma, Cystic**
*Axial T1 C+ MR shows a partly cystic, partly solid mass in the right CPA <img src='img/arrows/WS.png'/> and posterior Meckel cave <img src='img/arrows/WC.png'/>. Biopsy supported meningioma, which rarely may have cystic morphologies that mimic schwannoma.*